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中医肝病各证患者的血浆环核苷酸变化
引用本文:黎杏群,李学文,陈泽奇,石林阶,李家邦,胡随瑜,陈昌华,张海男,张翔,殷全荣,张花先.中医肝病各证患者的血浆环核苷酸变化[J].湖南中医药大学学报,2001,21(2):4-6.
作者姓名:黎杏群  李学文  陈泽奇  石林阶  李家邦  胡随瑜  陈昌华  张海男  张翔  殷全荣  张花先
作者单位:中南大学湘雅医学院,
基金项目:国家自然科学基金!资助重点项目 (39330 2 40 )
摘    要:用放射免疫法测定164例中医肝病各证型的血浆环核苷酸含量,与健康人37例比较,发现肝气郁结证、肝阳上亢证、肝阳化风证、肝火上炎证、肝血虚证均呈cGMP升高,cAMP变化无显著性差异。cAMP/cGMP比值降低,提示与植物性神经递质释放水平有关。

关 键 词:肝气郁结证  肝阳上亢证  肝阳化风证  肝火上炎证  肝血虚  环核苷酸  肝病  中医
文章编号:1000-5633(2001)02-0004-03
修稿时间:2000年10月10

Plasma Cyclic Nucleotide Alteration In Patients with Different Gan Zheng
Li Xingqun,Li Xuewen,Chen Zeqi,et al.Plasma Cyclic Nucleotide Alteration In Patients with Different Gan Zheng[J].Journal of Traditional Chinese Medicine University of Hunan,2001,21(2):4-6.
Authors:Li Xingqun  Li Xuewen  Chen Zeqi  
Abstract:We determined cAMP,cGMP concentration in plasma by radioimmunoassay in 164 cases of different syndromes of hepatopathy (Gan Zheng) (29 cases of Ganqiyujie Zheng (GQRJZ),17 of Ganyangshangkang Zheng (GYSKZ),32 of Ganyanghuafeng Zheng (GYHFZ),59 of Ganhuoshangyan Zheng (GHSYZ) and 27 of Ganxuexu Zheng (GXXZ)) Compared with 37 healthy controls,it was found that the contents of cGMP in plasma of all the patients with above five Zheng were increased and the cAMP/cGMP ratio decreased significantly,but the contents of cAMP in all Zheng showed no significant difference The results suggest that plasma cyclic nucleotide alteration might be related to increased release of catecholmines in Gan Zheng as a manifestion of sympathetic hyperfunction
Keywords:Gangqiyujie Zheng  Ganyangshangkang Zheng  Ganyanghuafeng Zheng  Ganhuoshangyan Zheng  Ganxuexu Zheng  blood  cyclic nucleotides
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