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类风湿伴肺间质改变患者血中Ⅲ型前胶原变化的研究
引用本文:徐波. 类风湿伴肺间质改变患者血中Ⅲ型前胶原变化的研究[J]. 卫生研究, 2002, 31(1): 60-61
作者姓名:徐波
作者单位:北京友谊医院呼吸内科,北京,100050
摘    要:
用放免法检测 30例类风湿关节炎伴或不伴肺间质病变的患者血中Ⅲ型前胶原含量 ,并以 15例正常人为对照。结果显示 ,类风湿关节炎患者 ,血中Ⅲ型前胶原明显高于正常对照组 ,且类风湿关节炎伴肺间质改变患者的血中Ⅲ型前胶原含量也高于类风湿关节炎无肺间质改变者。提示 ,类风湿关节炎患者易合并肺间质病变 ,且Ⅲ型前胶原水平变化对反映其是否合并肺间质病变具有一定敏感性。

关 键 词:Ⅲ型前胶原  类风湿关节炎  肺间质病变
文章编号:1000-8020(2002)01-0060-01
修稿时间:2001-06-11

Determination of serum type Ⅲ procollagen in patients with rheumatoid arthritis and interstitial lung disease
Xu BoBeijing Friendship Hospital,Beijing ,China. Determination of serum type Ⅲ procollagen in patients with rheumatoid arthritis and interstitial lung disease[J]. Journal of hygiene research, 2002, 31(1): 60-61
Authors:Xu BoBeijing Friendship Hospital  Beijing   China
Affiliation:Beijing Friendship Hospital, Beijing 100050, China.
Abstract:
Type III serum procollagen (Pc III) was measured by radio-immunossay in 30 rheumatoid arthritis(RA) patients with or without intestitial lung disease(ILD) and in 15 normal control subjects. The results showed that Pc III of RA patients were significantly higher than that of normal controls. Pc III levels is higher in RA patients with ILD than that in RA patients without ILD. The results suggested that RA patients with higher serum Pc III is more vulnerable to ILD, and the determination of Pc III might be valuable to show the complicated ILD.
Keywords:type Ⅲ procollagen (PcⅢ)   rheumatoid arthritis (RA)   interstitial lung disease (ILD)
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