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History of haemophilia
Authors:L. M. ALEDORT
Affiliation:Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY, USA
Abstract:Summary.  Haemophilia, an ancient disease, now has sophisticated methods for diagnosis and treatment. The genetically missing factors can now be supplied by fractionation of human-derived (HD) plasma or with recombinant technology (r). Making therapeutic choices is complicated by past transfusion-transmitted diseases. HD and r products now have similar safety profiles. Several diseases have only HD products for treatment. These products remain important in our treatment armamentarium.
Keywords:haemophilia    inhibitors    recombinant and human-derived factors    Von Willebrand disease
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