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立体定向扣带回毁损术治疗晚期癌痛
引用本文:张佩斯,刘会,王天成.立体定向扣带回毁损术治疗晚期癌痛[J].现代肿瘤医学,2014(3):670-672.
作者姓名:张佩斯  刘会  王天成
作者单位:辽宁省人民医院神经外一科,辽宁沈阳110016
摘    要:目的:探索扣带回毁损术治疗晚期癌痛的效果.方法:选择应用三阶梯治疗无效的晚期癌痛病人39例,包括肺癌20例,肝癌骨转移8例,前列腺癌骨转移6例,骨肿瘤患者5例,其中35例伴抑郁症及焦虑症.采用直观模拟疼痛量表(VAS)和McGill疼痛问卷量表(MPQ)分别在术前和书后进行疼痛评分,同时记录手术前后患者使用止痛药的种类和最大剂量,将术后3个月的VAS、MPQ评分与术前评分进行比较.结果:术后患者癌痛基本消失,只需服用小剂量止痛药物.术后3个月止痛效果稳定,VAS评分及MPQ评分较术前明显降低(P<0.05),无严重并发症发生,其中35例患者的抑郁症及焦虑症明显好转.结论:双侧扣带回前部联合毁损术能有效治疗晚期癌痛,缓解患者的抑郁症及焦虑症.

关 键 词:晚期癌痛  扣带回毁损  抑郁症  焦虑症

Cancer pain treated by stereotactic cingulate cortex damaged
Institution:Zhang Peisi, Liu Hui, Wang Tianeheng( Department of Neurosurgery ,Liaoning Province People's Hospital ,Liaoning Shenyang 110016 ,China.)
Abstract:Objective:To explore the effect of cingalate cortex damage surgery treatlnent on cancer pain. Meth- ods: Of 39 cases,including 20 cases of lung cancer,8 liver cancer,6 cases of prostate cancer bone lnetastases, bone tumors in 5 cases. Using visual analog pain scale (VAS) and MeGill pain questionnaire scale (MPQ) to observe pain score. Results:Postoperative pain in patients disappeared. Stable analgesic effect in postoperative 3 months, VAS score MPQ score was significantly lower compared with preoperative (P 〈 0. 05) or less, no serious complications, 35 cases with depression anxiety symptoms were improved markedly. Conclusion: Bilateral aeg dalnaged joint is effective treat- ment for advanced cancer pian.
Keywords:cancer pain  cingulate gyrus damaged  depression  anxiety
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