311例超声筛查异常孕妇产前诊断及妊娠结局临床分析

目的探讨产前筛查中孕妇B超筛查异常与胎儿染色体异常的关系及其对妊娠结局的影响。方法对2010-01～2012-06间来我院进行产前诊断的311例B超筛查异常孕妇,在B超介导下行羊膜腔或脐静脉穿刺,对羊水或脐血进行染色体核型分析。研究B超筛查异常与染色体异常的关系,并追踪其妊娠结局。结果检出胎儿染色体异常53例,占17.04%,其中9例为非整倍体染色体异常,占16.98%,均及时终止妊娠;剖宫产率为42.77%,其中单脐动脉剖宫产率最高,比率为72.41%;引产率为16.08%,胎儿多发畸形引产率最高,比率为85.00%。结论在产前筛查中B超检查发现异常的,建议其及时做染色体核型分析,并进行处理,是降低出生缺陷的有效措施。

311 Cases of Ultrasound Screening and Prenatal Diagnosis and Analysis of the Clinical Pregnancy Outcome

Objective To investigate the prenatal screening in pregnant women B ultrasonic screening abnormal and the relationship between fetal chromosomal abnormalities,and its effect on pregnancy outcome.Methods During January 2010~June 2012 prenatal diagnosis of 311 cases of B ultrasonic screening abnormal pregnant women did B ultrasonic exceed mediated descending amniotic cavity or percutaneous umbilical vein to analyze chromosome karyotype of amniotic fluid or umbilical cord blood.The relationship between B ultrasonic screening abnormal and chromosome abnormality is researched,and the pregnancy outcome is tracked.Results Of 311 patients with statistics,53 cases were detected as fetal chromosomal abnormalities,taking up 17.04%,including 9 cases of non-The Times-chromosome abnormalities,16.98%,are timely termination of pregnancy;Cesarean section rate was 42.77%,the single umbilical artery cesarean section rate was the highest,72.41%;Induced labor rate was 16.08%,multiple malformation fetus induced labor rate was highest,85.00%.Conclusion If abnormal in the prenatal screening in B ultrasonic examination occurs,It is advised to do the chromosome karyotype analysis,and carry on the processing,which is an effective measure to reduce the birth defect.