Aged venous thrombi: radioimmunoimaging with fibrin-specific monoclonal antibody |
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Authors: | Rosebrough, SF Grossman, ZD McAfee, JG Kudryk, BJ Subramanian, G Ritter- Hrncirik, CA Witanowski, LS Tillapaugh-Fay, G Urrutia, E |
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Abstract: | Radioimmunoimaging of fresh canine venous thrombi with a murine monoclonal antibody specific for human and dog fibrin has been reported. Successful imaging of canine deep venous thrombi 1, 3, and 5 days old at the time of antibody injection is reported. Images were positive in all dogs, and the uptake of fibrin-specific antibody was equivalent to that of fresh thrombi. |
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