几丁糖预防周围神经术后粘连的临床疗效观察

目的：为了解决周围神经损伤手术后神经粘连问题，特别是周围神经断伤吻合术后，解决神经纤维的生长与预防粘连问题。方法：在动物实验成功的基础上，临床在周围神经损伤应用显微外科技术行束问松解或外膜一束膜缝合的基础上应用几丁糖局部注入。于手术后6个月至2年观察神经功能恢复情况。结果：共临床应用102例110条神经，按照分级评定神经功能恢复.结果应用几丁糖者周围神经功能恢复和运动神经传导速度及诱发电位波幅明显优于未应用几丁糖者。周围神经粘连术后恢复优良率达91．5％，周围神经断伤吻合术后优良率达84％，总优良率达86．4％。结论：几丁糖具有明确的预防周围神经术后粘连的作用同时能够促进神经纤维的生长；临床应用疗效确切。并可在周围神经损伤的手术中临床推广应用。

Clinical Observation of Chitosan Prevention of Peripheral Nerve Injuries Postoperative Adhesions

Objective:To solve problems of nerve adhesions after surgery on peripheral nerve injury,especially the growth of nerve fibers and the prevention of adhesion after surgery on off peripheral nerve injury.Methods:On the basis of success in animal experiments,to clinically apply Chitosan for partial injection after peripheral nerve injury surgery with microsurgical technique,which releases beams or sutures outer membrane-beam film.To observe the neurological recovery situation six months to two years after the ...