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~(13)C-尿素呼气试验诊断儿童幽门螺杆菌感染的临床评估
引用本文:楼金吐,陈肖肖,曲一平,虞燕萍,吴秀英,章许平. ~(13)C-尿素呼气试验诊断儿童幽门螺杆菌感染的临床评估[J]. 上海医学检验杂志, 2005, 0(2)
作者姓名:楼金吐  陈肖肖  曲一平  虞燕萍  吴秀英  章许平
作者单位:浙江大学医学院附属儿童医院 浙江杭州310003(楼金吐,陈肖肖,曲一平,虞燕萍,吴秀英),浙江大学医学院附属儿童医院 浙江杭州310003(章许平)
摘    要:
目的 评估13C 尿素呼气试验(13C UBT)诊断幽门螺杆菌(HP)感染的准确性。方法 对23例有消化 道症状的患儿进行病理组织学、快速尿素酶试验,以决定是否感染HP。结果 以内镜检查结果作为诊断HP感 染的金标准。13C UBT的敏感性是92.85%,特异性100%,阳性预测值100%,阴性预测值90%,诊断准确率 95.56%。结论 13C UBT有较高的敏感性和特异性,是一种测定小儿HP感染可靠易行的非侵入性诊断方法。

关 键 词:幽门螺杆菌  13C-尿素呼气试验  儿童

The clinical evaluation of ~(13)C-urea breath test for the diagnosis of the Helicobacter pylori in children infection
LOU Jintu,CHEN Xiaoxiao,QU Yiping,YU Yanping,WU Xiuying,ZHANG Xuping. The clinical evaluation of ~(13)C-urea breath test for the diagnosis of the Helicobacter pylori in children infection[J]. Shanghai Journal of Medical Laboratory Sciences, 2005, 0(2)
Authors:LOU Jintu  CHEN Xiaoxiao  QU Yiping  YU Yanping  WU Xiuying  ZHANG Xuping
Affiliation:LOU Jintu,CHEN Xiaoxiao,QU Yiping,YU Yanping,WU Xiuying,ZHANG Xuping. The Children's Hospital,College of Medical Sciences,Zhejiang University,Zhejiang Hangzhou 310003,China
Abstract:
Objective To evaluate the accuracy of the 13C-urea breath test ( 13C-UBT) in the diagnosis of Helicobacter pylori(HP). Methods Twenty-three children with digestive tract symptom were tested for HP using pathological histology and fast urea enzyme test. Results Using the endoscopic line checking as control, the sensibility of 13C-UBT was 92.85% and the specificity was 100%. The positive prediction, the negative prediction and the accuracy of diagnositic were 100%, 90% and 95.56% respectively. Conclusions The 13C-UBT has high sensibility and speciality. It is a reliable and manageable noninvasive diagnostic method in detecting the HP infection of children.
Keywords:Helicobacter pylori  13C-urea breath test  Child
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