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Ketogenic Diet as a Preventive and Supportive Care for COVID-19 Patients
Authors:Elena Gangitano  Rossella Tozzi  Orietta Gandini  Mikiko Watanabe  Sabrina Basciani  Stefania Mariani  Andrea Lenzi  Lucio Gnessi  Carla Lubrano
Institution:1.Department of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy; (M.W.); (S.B.); (S.M.); (A.L.); (L.G.);2.Department of Molecular Medicine, Sapienza University of Rome, 00161 Rome, Italy; (R.T.); (O.G.)
Abstract:Severe obesity is associated with an increased risk of admission to intensive care units and need for invasive mechanical ventilation in patients with COVID-19. The association of obesity and COVID-19 prognosis may be related to many different factors, such as chronic systemic inflammation, the predisposition to severe respiratory conditions and viral infections. The ketogenic diet is an approach that can be extremely effective in reducing body weight and visceral fat in the short term, preserving the lean mass and reducing systemic inflammation. Therefore, it is a precious preventive measure for severely obese people and may be considered as an adjuvant therapy for patients with respiratory compromise.
Keywords:SARS-CoV-2  COVID-19  obesity  ketogenic diet  VLCKD  inflammation  viral infections  respiratory failure
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