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重型肝炎合并真菌感染相关因素分析
引用本文:李月翠,胡伟跃,李进,骆红霞. 重型肝炎合并真菌感染相关因素分析[J]. 中国药房, 2011, 0(34): 3224-3227
作者姓名:李月翠  胡伟跃  李进  骆红霞
作者单位:浙江永康市第一人民医院;
摘    要:
目的:调查重型肝炎合并真菌感染的相关因素。方法:对2006年11月-2010年6月重型肝炎合并真菌感染住院患者进行前瞻性研究。结果:重型肝炎合并真菌感染率为26.1%(30/115),以白色念珠菌为主,占50.0%;感染部位以呼吸道为主,占76.7%;其感染因素为广谱抗菌药物、激素应用、白细胞减少、侵入性操作及疾病严重程度(P均<0.01);研究组与对照组病死率分别为70.0%(21/30)和50.6%(43/85)。多因素回归分析表明,死亡危险因素为侵入性操作、血白细胞减少和疾病严重程度。抗真菌治疗有效的患者肝功能呈好转趋势。结论:了解重型肝炎合并真菌感染的相关因素对疾病的预防、诊疗及预后改善具有重要意义。

关 键 词:重型肝炎  真菌感染  危险因素

Analysis of Related Factors of Severe Hepatitis Complicating with Fungal Infections
LI Yue-cui,HU Wei-yue,LI Jin,LUO Hong-xia. Analysis of Related Factors of Severe Hepatitis Complicating with Fungal Infections[J]. China Pharmacy, 2011, 0(34): 3224-3227
Authors:LI Yue-cui  HU Wei-yue  LI Jin  LUO Hong-xia
Affiliation:(Yongkang Municipal First People's Hospital of Zhejiang Province, Yongkang 321300, China)
Abstract:
OBJECTIVE:To study related factors of severe hepatitis complicating with fungal infections. METHODS:The data of severe hepatic patients with fungal infections from Nov. 2006 to Jun. 2010 were studied prospectively. RESULTS:The occurrence rate of severe hepatitis complicating with fungal infections was 26.1%(30/115). Candida albicans accounted for 50.0%. Infectious rate in respiratory tract was 76.7%. The application of broad-spectrum antibiotics and corticosteroids, neutropenia, all kinds of invasive operat...
Keywords:Severe hepatitis  Fungal infections  Risk factors  
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