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| 电感耦合等离子体质谱法检测尿液中镍、铬含量 | |
| 引用本文： | 李惠玲,马婧,郝凤桐. 电感耦合等离子体质谱法检测尿液中镍、铬含量[J]. 标记免疫分析与临床, 2010, 17(6): 389-391. DOI: 10.3969/j.issn.1006-1703.2010.06.016 |
| 作者姓名： | 李惠玲 马婧 郝凤桐 |
| 作者单位： | 北京朝阳医院,北京,100020;北京朝阳医院,北京,100020;北京朝阳医院,北京,100020 |
| 摘 要： | 本文就使用电感耦合等离子体质谱仪同时测定尿液中镍、铬元素含量的方法进行了研究。样品经简单稀释后直接进样,采用动态反应池技术消除离子干扰,并使用内标进行校正。尿液中镍、铬元素的检出限分别为0.06μg/L和0.001μg/L,检测相对标准偏差在1.4%~4.7%间,加标回收率为99.1%~102.4%,同时质控样品值也落入可信参考范围。本方法样品处理简单,测量快速、灵敏、准确,值得临床推广应用。 |
| 关 键 词： | 电感耦合等离子体质谱 动态反应池 烤瓷牙 尿液 镍 铬 |
Determination of Nickel and Chromium in Urine by Inductively Coupled Plasma Mass Spectrometry |
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| LI Hui-ling,MA Jing,HAO Feng-tong. Determination of Nickel and Chromium in Urine by Inductively Coupled Plasma Mass Spectrometry[J]. Labeled Immunoassays and Clinical Medicine, 2010, 17(6): 389-391. DOI: 10.3969/j.issn.1006-1703.2010.06.016 | |
| Authors: | LI Hui-ling MA Jing HAO Feng-tong |
| Affiliation: | LI Hui-ling,MA Jing,HAO Feng-tong(Beijing Chao-yang Hospital,Capital Medical University,Beijing 100020,China) |
| Abstract: | To develop a method on simultaneous determining Nickel and Chromium in urine by Inductively Coupled Plasma Mass Spectrometry(ICP-MS).The samples were diluted directly and analyzed by using an internal standard and the dynamic reaction cell technology eliminates the ion interference.The result showed that the detection limit of Nickel in urine is 0.06 μg/L and Chromium is 0.001μg/L,the relative standard deviation of Nickel and Chromium were between 1.4% and 4.7%,the recovery rates were between 95% and 106%,and the value of QC sample were in the acceptable ranges.The method developed in this study is simple,rapid,sensitive and accurate.It can be widely applied in clinical medicine. |
| Keywords: | Inductively coupled plasma mass spectrometry Dynamic reaction cell(DRC) Porcelain teeth Urine Nickel Chromium |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |