原发性肝癌患者与其一级亲属的血糖水平分析

目的]分析启东地区原发性肝癌患者与其一级亲属及对照者血糖水平。方法]肝癌患者448例（肝癌组）、肝癌患者一级亲属1282例（亲属组）及健康体检人员1236例（对照组），均作HBsAg、空腹血糖检测，以χ2检验进行统计学处理。结果]肝癌组的高血糖检出率显著性高于亲属组和对照组（χ2=16．64、64．80，P均〈0．01）；亲属组显著性高于对照组（χ2=24．33，P〈0．01）。肝癌组HBsAg阳性检出率显著性高于亲属组和对照组（χ2=382．91、726．61，P均〈0．01）；亲属组显著性高于对照组（χ2=91．04，P〈0．01）。结论]高血糖和HBsAg可能是原发性肝癌的独立或协同危险因素，肝癌患者的一级亲属也可能是原发性肝癌的易感人群，应予高度重视。

An Analysis of Blood Glucose Level in Patients with Liver Cancer and in Their First Degree Relatives

Purposel To analysis the blood glucose level in patients with liver cancer and in their first degree relatives. Method] Four hundred and forty-eight cases with liver cancer, 1282 cases of their first degree relatives, and 1236 healthy person as control were enrolled. The HBsAg and fasting blood glucose were detected. Chi-square test was used for statistic analysis. Results]The hyperglycemia rate in liver cancer group was significant higher than that in relatives group and control group （χ2=16.64,64.80, respectively, P all〈0.01）, and hyperglycemia rate in relatives group was higher than that in control group （χ2=24.33,P〈0.01）. The positive rate of HBsAg in liver cancer group was significant higher than that in relatives group and control group （χ2=382.91 and 726.61, respectively,P all 〈0.01） , and the positive rate in relatives group was higher than that in control group （χ2=91.04,P〈0.01）. Conclusionl High blood glucose level and HBsAg positivity may be independent or synergic risk factors for liver cancer. Perhaps the relatives of these patients are a group of people susceptible to liver cancer.Control and prevention should be enhanced.