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左卡尼汀联合曲美他嗪治疗老年缺血性心肌病心力衰竭的疗效观察
引用本文:钟淼,李婷婷,史若飞. 左卡尼汀联合曲美他嗪治疗老年缺血性心肌病心力衰竭的疗效观察[J]. 中国药房, 2010, 0(20): 1872-1874
作者姓名:钟淼  李婷婷  史若飞
作者单位:重庆市急救医疗中心老年科;
摘    要:
目的:观察左卡尼汀联合曲美他嗪治疗老年缺血性心肌病(ICM)心力衰竭的短期疗效。方法:选择老年ICM心力衰竭患者64例,随机分为对照组和观察组,各32例。2组患者均接受调脂、抗血小板和抗心肌缺血的基础治疗以及常规抗心衰治疗,观察组在此基础上静脉滴注左卡尼汀并口服曲美他嗪。疗程均为2周。观察2组患者治疗前后心功能分级、实验室检查各指标以及采用彩色多普勒超声测量左室舒张末内径(LVEDD)、左室收缩末内径(LVESD)及左室射血分数(LVEF)。结果:观察组的心功能、LVEDD、LVESD、LVEF明显优于对照组,差异有统计学意义(P<0.05),且无肝肾功能异常。结论:左卡尼汀联合曲美他嗪治疗老年ICM心力衰竭短期疗效显著,且无明显不良反应。

关 键 词:左卡尼汀  曲美他嗪  缺血性心肌病  心力衰竭  疗效观察

Clinical Efficacy of Levoearnitine Combined with Trimetazidine in the Treatment of Ischemic Cardiomyopathy Heart Failure in Elderly
ZHONG Miao,LI Ting-ting,SHI Ruo-fei. Clinical Efficacy of Levoearnitine Combined with Trimetazidine in the Treatment of Ischemic Cardiomyopathy Heart Failure in Elderly[J]. China Pharmacy, 2010, 0(20): 1872-1874
Authors:ZHONG Miao  LI Ting-ting  SHI Ruo-fei
Affiliation:ZHONG Miao,LI Ting-ting,SHI Ruo-fei(Dept.of Geriatrics,Chongqing Medical Treatment First Aid Center,Chongqing 400014,China)
Abstract:
OBJECTIVE:To explore clinical efficacy of levoearnitine combined with trimetazidine in the treatment of ischemic cardiomyopathy(ICM) heart failure in elderly patients.METHODS:64 ICM elderly patients with heart failure were randomly divided into control group and observation group(n=32).Both group were given therapy of regulating blood lipid,antiplatelet,anti ischemia and conventional anti-heart failure therapy.Observation group were additionally intravenously injected with levoearnitine and given oral dose ...
Keywords:Levoearnitine  Trimetazidine  Ischemic cardiomyopathy  Heart failure  Efficacy  
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