| 中医药干预干眼病的临床及实验研究进展 |
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| 引用本文： | 樊迪,邵美娟,杨芳明,杨晓倩,左建平. 中医药干预干眼病的临床及实验研究进展[J]. 上海中医药大学学报, 2019, 33(3): 88-92 |
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| 作者姓名： | 樊迪 邵美娟 杨芳明 杨晓倩 左建平 |
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| 作者单位： | 上海中医药大学科技实验中心;中国科学院上海药物研究所 |
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| 基金项目： | 国家自然科学基金资助项目(81673445)；国家重大新药创制科技专项项目(2017ZX09101002-002-010) |
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| 摘 要： | ![]()
综述中医药干预干眼病的临床及实验研究进展。临床研究方面,依据干眼病的病因病机,对肝肾阴虚型、肺阴不足型、肝郁阴虚型、肝旺脾虚型等不同证型的干眼病患者进行辨证论治,采用中药方剂内服、中药滴眼液外用、针灸等中医药疗法能显著改善患者的症状,增加其泪液分泌量,延长泪膜破裂时间;实验研究方面,多种中药复方、单味药、提取物及单体对药物(如东莨菪碱、阿托品、高渗盐水)和手术(如去势、腺体摘除)诱导的干眼病动物模型具有治疗作用,其作用机制与免疫、炎症、氧化应激、细胞凋亡、激素等相关。
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| 关 键 词： | 干眼病 中医药疗法 动物模型 机制 综述 |
| 收稿时间： | 2019-03-05 |
| 修稿时间： | 2019-03-14 |
Clinical and experimental research progress of traditional Chinese medicine in the treatment of dry eye disease |
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| FAN Di,SHAO Meijuan,YANG Fangming,YANG Xiaoqian and ZUO Jianping. Clinical and experimental research progress of traditional Chinese medicine in the treatment of dry eye disease[J]. Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai, 2019, 33(3): 88-92 |
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| Authors: | FAN Di SHAO Meijuan YANG Fangming YANG Xiaoqian ZUO Jianping |
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| Affiliation: | Experimental Center for Science and Technology,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China,Experimental Center for Science and Technology,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China,Experimental Center for Science and Technology,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China and Experimental Center for Science and Technology,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China |
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| Abstract: | ![]()
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| Keywords: | dry eye disease therapy of traditional Chinese medicine animal model mechanism review |
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