针刺治疗冠心病的疗效观察及其对冠状动脉斑块的影响

目的观察针刺治疗冠心病的临床疗效及其对冠状动脉斑块的影响。方法将80例冠心病患者随机分为治疗组和对照组,每组40例。对照组采用常规药物治疗,治疗组在对照组基础上采用针刺治疗。观察两组治疗前后各项血脂指标胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C)]、平均动脉压(MAP)、心率(HR)、心电图指标(V4、V5、V6导联T波振幅)、冠状动脉斑块各项指标血管重塑指数(RI)、斑块偏心指数(EI)、坏死核心面积(NC)]的变化情况,并比较两组临床疗效。结果治疗组总有效率为85.0%,对照组为62.5%,两组比较差异具有统计学意义(P<0.05)。两组治疗后各项血脂指标、MAP、HR、心电图指标及冠状动脉斑块各项指标与同组治疗前比较,差异均具有统计学意义(P<0.05)。治疗组治疗后TG、LDL-C、MAP、HR、心电图指标及冠状动脉斑块各项指标与对照组比较,差异均具有统计学意义(P<0.05)。结论针刺能明显改善冠心病患者血脂、血压、心率及心电图指标,减少冠状动脉斑块形成。

Observation on the Efficacy of Acupuncture in Treating Coronary Heart Disease and Its Effect on Coronary Artery Plaque

Objective To investigate the clinical effect of acupuncture in treating coronary heart disease(CHD)and its effect on coronary artery plaque.Method Eighty CHD patients were randomized to treatment and control groups,with 40 cases in each group.The control group was intervened by conventional medication,while the treatment group was additionally given acupuncture.Indicators of blood lipidsserum total cholesterol(TC),triacylglycerol(TG),low-density lipoprotein cholesterol(LDL-C)and high-density lipoprotein cholesterol(HDL-C)],mean arterial pressure(MAP),heart rate(HR),indicator of electrocardiogram(T-wave amplitude in leads V4-V6)and indicators of coronary artery plaquevascular remodeling index(RI),plaque eccentricity index(EI)and necrotic core(NC)]in the two groups were observed before and at the end of treatment,and the clinical efficacies of the two groups were compared.Result The total efficacy rate was 85.0%in the treatment group and 62.5%in the control group,and there was a statistically significant difference between the two groups(P<0.05).The indicators of blood lipids,MAP,HR,the indicator of electrocardiogram and the indicators of coronary artery plaque all showed a significant change after the treatment in the two groups(P<0.05).After the treatment,the indicators of blood lipids(TG,LDL-C),MAP,HR,the indicator of electrocardiogram and the indicators of coronary artery plaque in the treatment group were significantly different from those in the control group(P<0.05).Conclusion Acupuncture can significantly improve blood lipids,blood pressure,HR and the indicator of electrocardiogram in CHD patients,and reduce coronary artery plaque.