转铁蛋白与血红蛋白同时检测消化道出血

目的 探讨检查粪便中转铁蛋白（Tf)和血红蛋白（Hb)对诊断消化道出血性疾病的临床价值。方法 对46例健康人及135例有消化道出血疾病的患者粪便标本进行检测。用Quick Chaser便潜血法检测Tf和Hb;“速而准”便隐血法检测Hb;便潜血A,B板法检测Hb。结果 Quick Chaser便潜血法同时检测Tf和Hb,一项结果阳性者即为符合诊断。阳性率健康组2．2％,上消化道出血组40．2％,下消化道出血组68．4％;用“速面准”法检查人Hb,阳性率健康组2．2％,上消化道出血组33．0％,下消化道出血组55．3％,便潜血A,B板邻联甲苯胺（A）法阳性率健康人组19．6％,上消化道出血组26．8％,下消化道出血组26．3％;愈创木脂（B）法阳性率健康组人19．6％,上消化道出血组13．4％,下消化道出血组7．9％。结论 Quick Chaser法同时检测粪便中人Hb,Tf是诊断消化道出血性疾病更有效的一种实验方法。

Simultaneous determination of both transferrin and hemoglobin in the patient with digestive tract bleeding

Objectivie To approach the diagnosis of digestive tract bleeding by simultaneously determining both transferrin and hemoglobin in stool.Methods Occult blood in stool samples from 46 healthy subjects and 135 patients with digestive tract bleeding was examined by three methods:1.immunochemical tests for simultaneous determination of both transferrin and hemoglobin,2.immunochemical test for single determination of hemoglobin,and 3.chemical tests A (o dibenzidine) and B (guaiac) for hemoglobin.Results 1.By the method 1, either positive transferrin or positive hemoglobin was considered in accordance with the diagnosis of digestive tract bleeding. The positive percentage was 2.2% in healthy controls group while 40.2% in the patients with bleeding in upper digestive tract, 68.4% in the patients with bleeding in lower digestive tract.2.By the method 2,The percentage of single positive hemoglobin was 2.2% in healthy controls group while 33.0% in the patients with bleeding in upper digestive tract, 55.3% in the patients with bleeding in lower digestive tract.3.By the method 3A, positive percentage of hemoglobin was 19.6% in healthy controls group while 26.8% in the patients with bleeding in upper digestive tract, 26.3% in the patients with bleeding in lower digestive tract. By the method 3B, positive percentage was 19.6% in healthy controls group, while 13.4% in the patients with bleeding in upper digestive tract, 7.9% in the patients with bleeding in lower digestive tract.Conclusion Simultaneously checking transferrin and hemoglobin in stool samples by immunochemical test is more advantageous manner for the diagnosis of digestive tract bleeding.