48例Ⅱ型糖尿病人血脂分析

本文对非胰岛素依赖型糖尿病（ＮＩＤＤＭ）病人４８例与年龄，ＢＭＩ相当的１８例对照就血脂ＴＧ、ＴＣ，脂蛋白ＨＤＬ─Ｃ、ＬＤＬ─Ｃ，ＶＬＤＬ─Ｃ，载脂蛋白ＡＰＯＡＩ，ＡＰＯＢ水平进行比较。ＮＩＤＤＭ组ＴＧ、ＴＣ比对照组高，两组之间差异显著；脂蛋白和载脂蛋白检查ＨＤＬ─Ｃ和ＡＭＡＩ水平较对照组低，ＬＤＬ─Ｃ，ＶＬＤＬ─Ｃ和ＡＰＯＢ是ＮＩＤＤＭ较对照组高。由于ＨＤＬ─Ｃ降低，抗动脉硬化因素下降，ＬＤＬ─Ｃ升高是动脉粥样硬化危险因素升高，这是ＮＩＤＤＭ病人脂代谢不正常，动脉粥样硬化危险性大的原因。用ＡＰＯＡＩ／ＡＰＯＢ和ＬＤＬ─Ｃ／ＨＤＬ─Ｃ比值较单项测定结果的差别更显著，是判别ＮＩＤＤＭ病人动脉粥样硬化更良好的指标。

ANALYSIS ON BLOOD─FAT OF 48 NIDDM PATIENTS

The article made a compari son of 48 NIDDM patients with 18 controls of the same age3nd BMI between their leves of blood─fat TG,TC Lipoprotein HDL─C,LDL─C,VLDL─C,carrier lipoprotein APOAI and APOB.The TG and TC in the NIDDM group is higher,and the difference between the two groups was apparent:HDL─cand APOAI in the exami-nation of lipoprotein and carrier lipoprotein were lower in the former while LDL─C,VLDL─C and APOB was higher.As HDL─C Lowerd the anti─atheroma factors decreased andLDL─C rose as atheroma’s dangerous factors rose. This is why NIDDM patients run greaterrisks of atheroma vvhen they show abnormal lipometabolism. The difference of the rate ofAPOAI/APOB and LDL─C/HDL─Cin comparison with the result of single item examina-tion will be much more apparent so it is a very good indicator in judging atheroma for theNIDDM patients.