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| 固定化青霉素G酰化酶的初步研究 | |
| 引用本文： | 李明沄,唐晋丰,杨萸,沈正华,于莺. 固定化青霉素G酰化酶的初步研究[J]. 中国医药工业杂志, 1987, 0(5) |
| 作者姓名： | 李明沄 唐晋丰 杨萸 沈正华 于莺 |
| 作者单位： | 上海医药工业研究院生化室，上海医药工业研究院生化室，上海医药工业研究院生化室，上海医药工业研究院生化室，上海医药工业研究院生化室 |
| 摘 要： | 本文研究固定化青霉素G酰化酶的不同制备方法,比较了各种固定化青霉素G酰化酶的载体。实验表明:聚丙烯腈纤维和无机载体制成的固定化酶具有较高的酶比活力,而且表面积大,易于装柱,抗污染能力大,又能裂解高浓度青霉素 G 溶液生成6-APA。 |
| 关 键 词： | 青霉素酰化酶 聚丙烯腈纤维 载体 固定化 |
STUDIES ON THE IMMOBILIZATION OF PENICILLIN G ACYLASE |
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| LI Ming-yun TANG Jin-feng YANG Yu SHEN Zheng-hua Yu Ying. STUDIES ON THE IMMOBILIZATION OF PENICILLIN G ACYLASE[J]. , 1987, 0(5) | |
| Authors: | LI Ming-yun TANG Jin-feng YANG Yu SHEN Zheng-hua Yu Ying |
| Affiliation: | Shanghai Institute of Pharmaceutical Industry |
| Abstract: | Different methods for preparing immobilized penicillin G acylasewere studied and the different carriers compared.The results showed that thepolyacrylonitrile fibre and inorganic carrier were the best carriers.They possessednot only the highest specific activity of immobilized enzyme but also larger poresize,better fluidity and could be re-used many times. |
| Keywords: | penicillin G acylase immobilization polyacrylonitrile fiber |
| 本文献已被 CNKI 等数据库收录！ | |