机械通气时呼气末正压对中心静脉压的影响

目的探讨机械通气时不同水平呼气末正压（PEEP）对中心静脉压（CVP）的影响。方法采用前瞻性自身对照研究选取30例机械通气患者,经颈内静脉置入深静脉导管,在不同水平PEEP（0、2、4、6、8、10、12 cmH2O）时,分别测定CVP及心率（HR）、平均动脉压（MAP）、呼吸频率（RR）。结果 PEEP与CVP呈显著正相关;PEEP增加前后的HR、MAP和RR变化比较,差异无统计学意义。结论观察CVP值的动态变化趋势是使用CVP指导液体治疗的关键。

Mechanical Ventilation when Expiratory at the end of the Positive Pressure of the Central Venous Pressure Influence

Objective To evaluate the effect of positive end expirtory pressure（PEEP） on central venous pressure（CVP） in patients with mechanical ventilation.Methods This is a prospective self-controlled study-30 patients were enrolled in study with MV and CVP measurement in intensive care unit.CVP,heart rate（HR）,mean arterial pressure（MAP）,and respiration rate（RR） were obtained simultaneously under at various PEEP levels of 0、2、4、6、8、10 and 12 cmH2O.Results The CVP value got an increase with a rise of PEEP.There was asignificant positive correlation between CVP is the key to guide the fluid therapy.Conclusion The use of CVP to guide fluid therapy is the key to the observed CVP dynamic change trend.