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血小板激活因子拮抗剂银杏苦内酯B对烫伤大鼠心血管功能的影响
引用本文:殷明 方之扬. 血小板激活因子拮抗剂银杏苦内酯B对烫伤大鼠心血管功能的影响[J]. 第二军医大学学报, 1990, 11(3): 210-212
作者姓名:殷明 方之扬
作者单位:长海医院烧伤科(殷明,方之扬,葛绳德,刘世康),长海医院烧伤科(陈玉林)
摘    要:


关 键 词:PAF 银杏苦内酯B 烧伤 拮抗剂

Effects of PAF Antagonist Ginkgolide B on Cardiovascular Parameters of Thermally Injured Rats
Yin Ming,et al. Effects of PAF Antagonist Ginkgolide B on Cardiovascular Parameters of Thermally Injured Rats[J]. Former Academic Journal of Second Military Medical University, 1990, 11(3): 210-212
Authors:Yin Ming  et al
Abstract:
Platelet-activating factor (PAF), when given to rats (200 ng/kg, iv) induced rapid decrease of BP, LVSP and dp/dt which was antagonized by pretreatment of ginkgolidc B (5 mg/kg.iv). Bioassas showed higher PAF level in the scalded rats (P<0.05 or 0.01) than that in the unscalded control group. Cardiovascular indexes of ginkgolide B-treated rats maintained at higher level than those of the control group. These results suggest that PAF may be partly responsible for the decrease of (?) cardiovascular parameters of the scalded rats.
Keywords:platelet-activating factor  ginkgolide B  burn  rats
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