Abstract: | Background: Guidelines for high‐level disinfection of gastrointestinal endoscopes have been published in many countries; however, none of them have a statement for disinfection against the parasite Strongyloides stercoralis. To establish a method for gastrointestinal endoscope disinfection against Strongyloides stercoralis, we examined the disinfection efficacy of high‐level disinfectants (3% glutaraldehyde, 0.55% ortho‐phthalaldehyde, and 0.3% peracetic acid) and 70% ethanol by in vitro tests. Methods: Strongyloides stercoralis larval suspension (0.05 mL) was added to 0.95 mL of each disinfectant and disinfection time measured under low magnification microscopy. Results: Among the high‐level disinfectants, peracetic acid was more efficacious for disinfection against Strongyloides stercoralis than glutaraldehyde and ortho‐phthalaldehyde. Ethanol was also efficacious for parasite killing. Conclusion: These results suggested that peracetic acid be recommended for gastrointestinal endoscope disinfection in regions with endemic Strongyloides stercoralis. |