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| 正交试验优选疗筋涂膜剂醇提工艺 | |
| 引用本文： | 李得堂,唐洪梅,黄樱华,丘振文. 正交试验优选疗筋涂膜剂醇提工艺[J]. 中国药房, 2008, 19(18): 1379-1381 |
| 作者姓名： | 李得堂 唐洪梅 黄樱华 丘振文 |
| 作者单位： | 1. 广州中医药大学,广州市,510405 2. 广州中医药大学第一附属医院,广州市,510405 |
| 摘 要： | 目的:优选疗筋涂膜剂的醇提工艺。方法:以醇浸膏得率和大黄素含量为考察指标,采用正交试验法,考查乙醇浓度、加醇量及提取时间对提取工艺的影响。结果:最佳醇提工艺为A2B2C2,即药材加6倍量70%乙醇提取2次,第1次提取1.5h,第2次提取1h。结论:优选的疗筋涂膜剂的醇提工艺简便、快速、准确,可为工业化生产提供理论依据。 |
| 关 键 词： | 正交试验 疗筋涂膜剂 醇提工艺 浸膏得率 大黄素 |
Optimization of Ethanol Extract Technology for Liaojin Membrane by Orthogonal Test |
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| LI De-tang,TANG Hong-mei,HUANG Yin-hua,QIU Zhen-wen. Optimization of Ethanol Extract Technology for Liaojin Membrane by Orthogonal Test[J]. China Pharmacy, 2008, 19(18): 1379-1381 | |
| Authors: | LI De-tang TANG Hong-mei HUANG Yin-hua QIU Zhen-wen |
| Affiliation: | LI De-tang,TANG Hong-mei, HUANG Yin-hua, QIU Zhen-wen(Guangzhou University of TCM, Guangzhou 510405, China;The First Affiliated Hospital of Guangzhou University of TCM, Guangzhou 510405,China) |
| Abstract: | OBJECTIVE： To optimize the ethanol extract technology of Liaojin membranes. METHODS： Alcohol extract rate and Emodin content were taken as the indexes for investigation and orthogonal test was carried out to investigate the effects of three extracting factors （alcohol density, alcohol amount and extracting time） on the extract technology. RESULTS： The optimum extract technology was A2B2C2, i.e. adding 70% alcohol which was 6 times the quantity of medicine and extracting twice （1.5h the first time and lh the second time） . CONCLUSION： The optimized ethanol extracttechnology for Liaojin membranes is simple, rapid and accurate, and serves as theoretic basis for the industrialized production of this preparation. |
| Keywords: | Orthogonal test Liaojin membranes Ethanol extract technology Extract rate Emodin |
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