精液白细胞对精液主要参数及精子功能的影响分析

目的探讨精液白细胞含量与精液主要参数和指标的关系。方法按照WHO人类精液实验室手册要求检测精液中的白细胞、主要参数、精子形态分析、精子顶体酶活性、精浆抗体（AsAb）、解脲支原体等，分析精液白细胞与男性不育相关因素的关系。结果238例男性不育患者中有75例（31．5％）精液中白细胞〉1×10^6个／ml，设为白细胞精子组；163例（68．5％）患者精液中白细胞≤1×10^6个／ml，设为非白细胞精子组。白细胞精子组的精子密度、精子活动率、a＋b级活力精子率、精子顶体酶阳性率均低于非白细胞精子组（P〈0．05）；而精子畸形率、精浆抗体（AsAb）、解脲支原体阳性率均高于非白细胞精子组（P〈0．05）。两组的精液量、pH值和液化时间差异无显著性。结论精液中白细胞含量与精液质量有密切的关系，是导致男性不育的重要原因。

The influence of semen white blood cells on semen major parameters and sperm function

Objective： To study the relationship between semen white blood cells （WBC） and semen major parameters. Methods： Semen WBC, major parameters, abnormal morphological sperm rate, sperm acrosin reaction, AsAb and UU infection were measured and analyzed in 238 infertile men according to WHO laboratory handbook about human semen. Results： Semen WBC 〉 1×10^6/ml were 75 cases in 238 male,infertility, set up into WBC positive group; Semen WBC≤ 1×10^6/ml were 163 cases, set up into WBC negative group. Semen concentration, motility, a＋b grade motility, and sperm acrosin reaction rate in WBC positive group were lower than in WBC negative group （ P〈0.05） ; Higher abnormal morphological sperm, UU infection rate and AsAb positive rate were observed in WBC positive group （ P〈0.05） ; Sperm volume, pH value and liquefying time were not significantly different between WBC positive and negative group （ P〉0.05）. Conclusion ： Sperm WBC have effect on sperm quality, which can be considered as one of the important reasons resulting in male infertility.