自体瘤苗综合治疗原发性肝癌12例临床报告

为了研究自体瘤苗在原发性肝癌综合治疗中的临床价值,总结１９８８ 年至１９８９ 年间采用手术切除和自体瘤苗回植法综合治疗原发性肝癌１２ 例的临床结果。研究方法采用新鲜离体肝癌组织经液氮冷冻灭活后制成自体瘤苗,于术后定期反复回植患者体内,随访观察患者治疗后的生存时间和生存质量。结果显示,１２ 例原发性肝癌患者经上述综合治疗后,１２ 、３６、６０ 个月的生存率分别为１００．０ ％（１２／１２）、８３．３ ％（１０／１２） 和５８．２％ （７／１２）。有３ 例患者至今已无瘤生存１０５ ～１２１ 个月,并能坚持日常工作。结果表明,原发性肝癌患者常规切除术后综合自体瘤苗回植,对延长其生存时间和提高其生存质量具有实际意义

Treating Primary Liver Cancer by Comprehensive Therapy with Auto tumour Vaccine,Report of 12 cases

From 1988 to 1989,12 cases of primary liver cancer were treated by auto tumour vaccine replantation after surgery section.The fresh tumour tissue masses were inactivated by freezing in liquid nitrogen for vaccine making.The vaccine was replanted to the patients repeatedly with certain interval periods.Survival time and life quality were surveyed after surgery sections.Results showed that the 12 months,36 months and 60 months survival rates were 100%(12/12),83.3%(10/12) and 58.3%(7/12),respectively.Among the 12 cases,3 were still alive and able to work in their usual position.It was suggested that auto tumour vaccine replantation following routine surgery section could induce survival time prolonged and rise up their survival quality.