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| 厄贝沙坦对高血压患者血压及微量白蛋白尿的影响 | |
| 引用本文： | 徐新春,张慧,朱福. 厄贝沙坦对高血压患者血压及微量白蛋白尿的影响[J]. 中国临床实用医学, 2008, 2(10): 42-43 |
| 作者姓名： | 徐新春 张慧 朱福 |
| 作者单位： | 1. 200031,上海市徐汇区中心医院中医科 2. 200031,上海市徐汇区中心医院老年科 |
| 摘 要： | 目的观察厄贝沙坦的降压疗效及对高血压患者尿微量白蛋白的影响。方法将115例患者随机分为3组，A组口服厄贝沙坦150mg／a，B组口服厄贝沙坦300mg／d，C组口服氨氯地平5mg／d，疗程6个月。治疗前后分别观察患者血压、尿微量白蛋白及肝肾功能。结果3组治疗后血压都明显下降，A组和B组治疗6个月后患者尿微量白蛋白明显下降（P〈0．05或P〈0．01），C组治疗后尿微量蛋白虽有下降，但差异无统计学意义（P〉0．05）。结论厄贝沙坦具有平稳的降压疗效，并具有肾保护作用。 |
| 关 键 词： | 高血压 厄贝沙坦 尿微量蛋白 |
Effect of irbesartan on bloodpressure and microalbuminuria in patients with essential hypertension |
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| XU Xin-chun,ZHANG Hui,ZHU Fu. Effect of irbesartan on bloodpressure and microalbuminuria in patients with essential hypertension[J]. China Clinical Practical Medicine, 2008, 2(10): 42-43 | |
| Authors: | XU Xin-chun ZHANG Hui ZHU Fu |
| Abstract: | Objective To observe the effecfion of irbersartan on bloodpressure and microalbuminuria in patients with hypertension.Methods 115 cares randomly assigned to receive irbesartan(150 mg/d)or irbesartan(300 me/d)or amlodipine(5 me/d)for 6 months.The bloodpressure,microalbuminuria,function of liver and kidney were observed before and after treatment.ResultsSBP/DBP was decreased significantly in the three groups.Mieroalbuminuria wes decreased significantly in patients treated with irbesartan(P＜0.05 or P＜0.01).There was no significant difference on microalbuminuria in amlodipine group.Conclusion irbesartan was pmved to be a stable.safe and effective antihypertensive medication and has renal protective effects. |
| Keywords: | Hypertension Lrbesartan Miemalbuminuria |
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