接骨止痛片醇提取工艺优选

目的:探讨接骨止痛片中骨碎补、续断、红花、土蟞虫醇提取工艺.方法:采用正交试验法,对接骨止痛片主要成分的醇提取条件进行优选.以醇浸膏得率,柚皮苷提取量为考查指标,对乙醇体积分数、加醇量、提取时间进行了优选.结果:最佳醇提取工艺为药材加80％乙醇回流提取2次,第1次加6倍量提取2h,第2次加5倍量提取1.5h.结论:接骨止痛片的醇提工艺合理,稳定.

Optimization of Extraction Technology for Jiegu Zhitong Tablet

Objective: To investigate alcohol extraction technology of Drynaria fortunei,Radix dipsaci, Flos carthami,Eupolyphaga seu steleophaga from Jiegu Zhitong tablet. Method: Orthogonal method was used to optimize alcohol extraction conditions of main ingredients from Jieguzhitong tablet.Took yield of alcohol extracts, extraction of naringin as indexes to optimize ethanol concentration, alcohol volume,extraction time. Result: Optimum extraction technology was as follows:reflux extracted 2 times with 80% ethanol,the first time extracted 2 h with 6 times the amount of 80% ethanol,then extracted 1.5 h with 5 times in second time. Conclusion: The extraction technology of Jiegu Zhitong tablet was stable and feasible.