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氨甲喋呤治疗异位妊娠两种肌肉注射方案的临床比较
引用本文:周荣向,杨军,叶海燕. 氨甲喋呤治疗异位妊娠两种肌肉注射方案的临床比较[J]. 中国妇幼保健, 2007, 22(28): 3983-3984
作者姓名:周荣向  杨军  叶海燕
作者单位:1. 解放军第421医院妇产科,广东,广州,510310
2. 解放军91708部队卫生防疫检验所
3. 广东省人民医院妇产科,510318
摘    要:目的:比较异位妊娠患者使用氨甲喋呤(MTX)单次肌肉注射和分次肌肉注射方案的治疗效果。方法:对两组异位妊娠患者的年龄、血β-HCG、异位妊娠包块大小、住院天数、治疗结果等进行比较。结果:单次肌肉注射和分次肌肉注射治疗方案的成功率分别是86.11%和87.50%,两者比较无显著性差异。结论:氨甲喋呤单次肌肉注射方案和分次肌肉注射方案疗效相当,但单次肌肉注射方案给药方便,更易为患者接受。

关 键 词:氨甲喋呤  异位妊娠  疗效
文章编号:1001-4411(2007)28-3983-02
修稿时间:2006-04-23

Comparison of different intramusculary protocol in the treatment of ectopic pregnancy with methotrexate
ZHOU Rong-Xiang,YANG Jun,YE Hai-Yan. Comparison of different intramusculary protocol in the treatment of ectopic pregnancy with methotrexate[J]. Maternal and Child Health Care of China, 2007, 22(28): 3983-3984
Authors:ZHOU Rong-Xiang  YANG Jun  YE Hai-Yan
Affiliation:Department of Obstetrics and Gynecology, No. 421 Hospital of PLA, Guangzhou 510318, Guangdong , China
Abstract:Objective:To compare efficacy of ectopic pregnancy patients treated with single-dose or multidose methotrexate(MTX)protocols.Methods:The age of patient,gestational age,serum human chorionic gonadotropin,overall ectopic mass size,history of ectopic pregnancy,number of treatment days in hospital,and outcome in consecutive patients with ectopic pregnancy treated with methotrexate were compared.Results:Successful rates were 86.11% and 87.5% respectively,there were no significantly differences.Conclusion:Single-dose methotrexate protocols is as effective as multidose methotrexate protocols,but the former is more convenient than the latter.
Keywords:Ectopic pregnancy  Methotrexate  Human chorionic gonadotropin  Ectopic pregnancy rupture
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