结节性甲状腺肿合并甲状腺癌25例

目的：探讨结节性甲状腺肿中甲状腺癌的临床特征和预后。方法：回顾性分析手术治疗结节性甲状腺肿合并甲状腺癌２５例临床资料。结果：２５例结节性甲状腺肿合并甲状腺癌，男６例，女１９例，年龄１２～６５（３６．８±１３．１）岁，占同期手术治疗３９５５例结节性甲状腺肿的０．６３％。术前、术中诊断甲状腺癌的占３２％，６８％为术后病理检查发现。甲状腺微小癌占４８％。结论：结节性甲状腺肿合并甲状腺癌预后较好。不能简单地认为结节性甲状腺肿是良性病变而忽略对其的处理，也不应过分强调甲状腺癌在治疗结节性甲状腺肿中的地位随意放宽手术指征，或扩大手术。

Thyroid carcinoma in nodular goiter

Objective :To assess the clinical characteristics and prognosis of thyroid carcinoma in nodular goiter. Methods:Retrospective analysis of surgical management was performed on patients with thyroid carcinomas in nodular goiter during a passed 10-year period. Results: Twenty-five of 3955 (0.63%) patients,19 females and 6 males,aged 12-65 years (mean =36.8 ?13.1 years), carried malignancy. The frequency of discovered carcinoma before or during surgery was 32%,68% of them was found incidentally by postoperative pathologic examination. Forty-eight percent of them were papillary thyroid microcarcinoma. Conclusion : Most patients with thyroid cancer in nodular goiter have an excellent prognosis. Nodular goiter should no longer be simply considered a benign disease, it should always be carefully thought about combination of carcinoma but not overemphasized, the policy of surgically treating all patients with nodular goiter and increase the extent of surgical excision is not Justified.