| 阿仑膦酸钠肠溶片对绝经后骨质疏松症 的疗效观察 |
| |
| 引用本文： | 汪冉,赵志芳,杨永宏,张冬生. 阿仑膦酸钠肠溶片对绝经后骨质疏松症 的疗效观察[J]. 中国骨质疏松杂志, 2012, 18(3): 273-275 |
| |
| 作者姓名： | 汪冉 赵志芳 杨永宏 张冬生 |
| |
| 作者单位： | 中国人民解放军第一一七医院骨一科, 杭州,310013 |
| |
| 摘 要： | 目的观察阿仑膦酸钠(石家庄欧意药业有限公司生产的"固邦")治疗绝经后骨质疏松症的临床疗效。方法选取80例绝经后骨质疏松症患者应用阿仑膦酸钠肠溶片治疗12个月,于治疗前后测定肝肾功能、ALP、骨钙素、尿NTX及腰椎、股骨颈、Wards三角区骨密度。结果应用阿仑膦酸钠肠溶片治疗12个月后患者骨密度较前升高(P<0.01),尿NTX(T值4.499)及ALP(碱性磷酸酶)(T值9.833)较治疗前降低(P<0.05)。结论阿仑膦酸钠肠溶片对绝经后骨质疏松症患者的治疗是有效的,不良反应少,且依从性好。
|
| 关 键 词： | 阿仑膦酸钠肠溶片 绝经 骨质疏松 |
Efficacy observation of alendronate sodium enteric-coated tablet on postmenopausal osteoporosis |
| |
| WANG Ran,ZHAO Zhifang,YANG Yonghong,and Zhang Dongsheng. Efficacy observation of alendronate sodium enteric-coated tablet on postmenopausal osteoporosis[J]. Chinese Journal of Osteoporosis, 2012, 18(3): 273-275 |
| |
| Authors: | WANG Ran ZHAO Zhifang YANG Yonghong and Zhang Dongsheng |
| |
| Affiliation: | WANG Ran,ZHAO Zhifang,YANG Yonghong,et al.First Department of Orthopedics,The 117th Hospital of PLA,Hangzhou 310013,China |
| |
| Abstract: | Objective To observe the clinical efficacy of alendronate for the treatment of postmenopausal osteoporosis.Methods Eighty postmenopausal osteoporosis patients were chosen and treated with alendronate sodium enteric-coated tablets for 12 months.The liver and kidney function,ALP,osteocalcin,urinary NTX,and bone mineral density(BMD) of the lumbar spine,femur neck,and Wards triangle were measured before and after the treatment.Results BMD increased after the 12-month treatment(P<0.01).However,urinary NTX(T=4.499) and ALP(T=9.833) decreased after the 12-month treatment(P<0.05).Conclusion Alendronate sodium enteric coated tablets for the treatment of postmenopausal osteoporosis is effective with little adverse reaction and good compliance. |
| |
| Keywords: | Alendronate sodium enteric-coated tablets Postmenopausal Osteoporosis |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
| 点击此处可从《中国骨质疏松杂志》浏览原始摘要信息 |
|
点击此处可从《中国骨质疏松杂志》下载全文 |
|
