硬膜外麻醉复合全身麻醉用于直肠癌根治手术麻醉效果观察

目的探讨硬膜外麻醉复合全身麻醉用于直肠癌根治术的麻醉效果。方法本研究回顾性纳入2010年6月至2012年6月期间在巴中市中心医院接受直肠癌根治术并符合本研究纳入条件的直肠癌患者共178例,其中男84例,女94例;年龄34～72岁,（51.9±10.255）岁;按麻醉方式分为单纯全身麻醉组（93例）和硬膜外麻醉复合全身麻醉组（85例）,观察2组的麻醉效果及不良反应。结果 2组一般基线资料比较,差异无统计学意义（P〉0.05）。2组的麻醉效果比较差异无统计学意义（P〉0.05）。从麻醉不良反应来看,硬膜外麻醉复合全身麻醉组在高血压、低血压、心动过速及术后恶心呕吐发生率方面均明显低于单纯全身麻醉组（P〈0.05）,2组在心动过缓、室性早搏发生率及胃肠道恢复时间方面比较差异无统计学意义（P〉0.05）,2组均无下肢神经功能异常发生。结论硬膜外麻醉复合全身麻醉用于直肠癌根治术与单纯全身麻醉相比,不仅能取得相同的麻醉效果,在减少麻醉不良反应方面也具有明显优势。

Anesthetic Quality of Epidural Anesthesia with General Anesthesia Applied for Surgery of Rectal Cancer

Objective To explore anesthetic quality of epidural anesthesia with general anesthesia applied for surgery of rectal cancer.Methods One hundred and seventy-eight patients who were diagnosed as rectal cancer and received operation in the Central Hospital of Bazhong City from June 2010 to June 2012 were included retrospectively.These patients were divided into two groups according to the type of anesthesia,and the patients who received general anesthesia only were defined as group A,the patients who received epidural anesthesia with general anesthesia were defined as group B.The anesthetic quality and anesthetic adverse reaction were observed in two groups.Results The differences of baseline characteristics in two groups were not significant（P0.05）.The difference of anesthetic quality in two groups was not significant（P0.05）.In terms of anesthetic adverse reaction,the incidence rate of hypertension,hypotension,tachycardia,or postoperative nausea and vomiting of the group B was significantly lower than those of the group A（P 0.05）.The incidence rate of bradycardia,premature ventricular contractions,or time of gastrointestinal function recovery had no significant differences（P 0.05）.There was no nerve dysfunction of lower limb in two groups.Conclusion Epidural anesthesia with general anesthesia applied for surgery of rectal cancer as compared with general anesthesia only not only has the same anesthetic quality,but also has obvious advantages in decreasing anesthetic adverse reaction.