乳腺导管原位癌的治疗现状与进展

目的总结乳腺导管原位癌的治疗现状与进展。方法查阅近年来关于乳腺导管原位癌治疗现状与进展的文献资料,并作综述。结果随着乳腺导管原位癌发病率的增加,其治疗方法也在不断演变。外科治疗包括全乳切除术和保乳术（BCS）。保乳术联合放疗被认为是标准的减少局部肿瘤复发的方法。内分泌治疗也在临床上得到了重视及应用。结论保乳术与综合治疗已成为乳腺导管原位癌治疗的主要方法,需要通过进一步的研究来确定何种乳腺导管原位癌亚组只需行BCS术而不需要其他的辅助治疗。微创治疗将是乳腺导管原位癌治疗的一个发展方向。

Actuality and Progress of Treatment for Ductal Carcinoma in Situ

Objective To summarize the current status and progress of treatment for ductal carcinoma in situ（DCIS）.Methods The related literatures on actuality and advancement of treatment for DCIS were searched and reviewed.Results As the increase of incidence,the treatment options for DCIS continued to evolve.Surgical treatment options included mastectomy and breast-conserving surgery.Postoperative radiation therapy in combination with breast-conserving surgery was considered to be the standard for the decrease of local recurrence.The role of endocrine therapy was also being evaluated currently.Conclusions Breast-conserving surgery and combined therapy have became the main methods for treatment of DCIS.Further studies are necessary to determine which subset of patients with DCIS require only surgery alone without adjuvant therapy.Minimally invasive treatment will be a developing direction of DCIS.