交互信息在心脏状态和心率研究中的应用

交互信息是一种检测系统之间相依性的方法 ,它可以同时检测线性和非线性相关。本文介绍了交互信息的计算方法和性质 ,讨论了它在单个时间序列上的应用 ,并将它应用于心脏状态研究上。利用实验动物的数据 ,我们发现了心搏的运动既不是随机的也不是周期的 ;并且 ,不同心脏状态下的交互信息有很大的差别 ,浅麻 ,机控呼吸和开胸状态下交互信息都相对较小 ,心肌损伤后有明显增大 ,提示心搏的交互信息与心脏健康程度有很大关系

APPLICATION OF MUTUAL INFORMATION IN INVESTIGATING HEART RATE AND CARDIAC STATE

Mutual information(MI) analysis is a general method to detect linear and nonlinear statistical dependencies between time series. This article showed the concept and the properties of MI, discussed the application of MI to one time-variable system, and applied MI to cardiac system. The heartbeat and cardiac state were found to be neither a random system nor a periodical system by using animal experimental data. We also found that the MI varied with changes of conditions. During anaesthesia, machine controlled breathing, and thoracotomy, MI was smaller than that during heart-hurt. It can be concluded that the MI was related to the health of the heart.