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| pH指示剂吸收度比值法测定克霉唑的含量 | |
| 引用本文： | 赵春杰,朱莉,张忠梅,金繁红,王香臣. pH指示剂吸收度比值法测定克霉唑的含量[J]. 沈阳药科大学学报, 1993, 0(1) |
| 作者姓名： | 赵春杰 朱莉 张忠梅 金繁红 王香臣 |
| 作者单位： | 沈阳药学院药物分析教研室(赵春杰，朱莉)，沈阳市红旗制药厂化验室(张忠梅，金繁红)，沈阳市红旗制药厂化验室(王香臣) |
| 摘 要： | 本文报道pH指示剂吸收度比值法测定克霉唑的含量。该法采用指示剂为稀溴酚蓝,测定波长433nm和599nm;标准液为0.1mol/L盐酸;仪器为日本岛津260型分光光度计。应用本法测定5批克霉唑含量,同时与药典法比较,结果一致。 |
| 关 键 词： | pH指示剂吸收度比值法 克霉唑 |
QUANTITATIVE DETERMINATION OF CLOTRIMAZOLE BY pH INDICATOR ABSORBANCE RATIO METHOD |
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| Zhao Chunjie Zhu Li Dept. of Pharmaceutical Anal.,Shenyang Coll. of Pharm. Zhang Zhongmei Jin Fanhong Wang Xiangchen Analytical Department,Hong Qi Pharmaceutical Factory. QUANTITATIVE DETERMINATION OF CLOTRIMAZOLE BY pH INDICATOR ABSORBANCE RATIO METHOD[J]. Journal of Shenyang Pharmaceutical University, 1993, 0(1) | |
| Authors: | Zhao Chunjie Zhu Li Dept. of Pharmaceutical Anal. Shenyang Coll. of Pharm. Zhang Zhongmei Jin Fanhong Wang Xiangchen Analytical Department Hong Qi Pharmaceutical Factory |
| Abstract: | The pH indicator absorbance ratio method was applied to the quantitative determination of clotrimazole. The determination was carried out easily, rapidly and accurately as follows:Bromophenol blue and the standard solution of 0.1 mol/L HC1 were used; the absorbances at 433nm and 599nm were measured. The contents of five batahes of clotrimazole were 98.8±0.22%, 99.3±0.23%, 99.2±0.33%, 99.3 ±0.15% and 100.0±0.14%, respectively. The method is comparable with the official quantitative analysis of clotrimazole. |
| Keywords: | The absorbance ratio method of pH indicator Clotrimazole |
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