颅内静脉系统血栓早期诊断及病因分析

目的探讨颅内静脉系统血栓形成的早期诊断方法及病因。方法对11例确诊为颅内静脉系统血栓患者的临床资料进行回顾性分析。结果临床主要表现为头痛10例，视乳头水肿8例，脑膜刺激征7例，意识障碍4例，抽搐3例，视力障碍2例；9例发现各种血液高凝因素；10例MRI＋MRV发现脑静脉或静脉窦异常信号，其中2例合并出血；早期抗凝及纤溶治疗治愈7例、好转3例、死亡1例。结论MRI＋MRV对颅内静脉系统血栓早期诊断具有重要意义，早期抗凝及纤溶治疗安全、效果好。

Early Diagnostic and Etiologic Analysis of Intracranial Venous Thrombosis

Objective To explore the early diagnosis and the etiology of intracranial venous thrombosis. Method The clinical data of 11 cases finally diagnosed intracranial venous thrombosis were retrospectively reviewed. Results The clinical manifestations were headache (10 cases), optic disc edema (8 cases), meningeal irritation sign (7 cases), conscious disturbance (4 cases), convulsion (3 cases) and visual disturbance (2 cases). Multiple blood coagulation enhancing factors were found in 9 patients. MRI and MRV images directly exhigited venous sinus occlusion and thrombosis in all the 10 cases. After early anticoagulation treatment, 7 cases were resolved, and 3 cases improved and 1 case died. Conclusion MRI+MRV plays an important role in the early diagnosis of intracranial venous thrombosis. Early anticoagulation treatment could improve the prognosis.