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Effects of secreted factors in culture medium of annulus fibrosus cells on microvascular endothelial cells: elucidating the possible pathomechanisms of matrix degradation and nerve in-growth in disc degeneration
Affiliation:2. Ferguson Laboratory for Orthopaedic Research, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA;3. Department of Neurosurgery, College of Medicine, Korea University, Seoul, Republic of Korea;4. Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan;6. Department of Orthopaedic Surgery, Center for Cellular and Molecular Engineering, University of Pittsburgh School of Medicine, 450 Technology Drive, Pittsburgh, PA 15219, USA;5. Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA 15261, USA
Abstract:
Keywords:Intervertebral disc degeneration  Angiogenesis  Tip cells  Annulus fibrosus  Endothelial cells  Metalloproteinases
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