福建省2007-2011年恶性肿瘤死亡流行病学特征及变化趋势分析

目的分析福建省恶性肿瘤死亡流行病学特征及其变化趋势。方法收集福建省死因监测系统2007-2011年数据,采用趋势χ2检验对性别、地区、年龄分布特征及死亡趋势进行分析。结果恶性肿瘤死亡为2007-2011年福建省居民首位死因,年均死亡率为149.80/10万,死亡率呈上升趋势（趋势χ2=71.329,P〈0.01）。无论男女城乡,死亡率均呈明显上升趋势（趋势χ2男=60.88,趋势χ2女=13.72,趋势χ2城市=17.20,趋势χ2农村=54.03,均P〈0.01）。男性死亡率（200.77/10万）明显高于女性（97.46/10万）（χ2=3703.97,P〈0.01）,城市死亡率（157.49/10万）明显高于农村（147.10/10万）（χ2=28.827,P〈0.01）。前10位恶性肿瘤依次为肝癌、肺癌、胃癌、食管癌、结直肠癌、白血病、乳腺癌、鼻咽癌、恶性淋巴瘤、胰腺癌。肝癌为男性和农村首位恶性肿瘤,肺癌为女性和城市首位恶性肿瘤。结论福建省恶性肿瘤死亡水平呈上升趋势,肝癌、肺癌、胃癌、食管癌、结直肠癌是监测重点,应考虑性别、年龄、地区分布特点及变化趋势来制定防控措施。

Epidemiological characteristics and trend of death among patients with malignant tumor in Fujian from 2007 to 2011

Objective To understand the epidemiological characteristics and trend of death among patients with malignant tumor in Fujian. Methods Based on data recorded in the cause of death surveillance system from 2007 to 2011, trend chi-square test was used to analyze the information of gender, age and region distribution and death trend of patients with malignant tumor. Results Malignant disease was the number one killer of residents in Fujian from 2007 to 2011 with the average annual mortality of 149.80 per 100 thousands popula tion and the overall rate kept going up each year （x2=71. 329, P〈 0.01）. The death rates of men and women, regardless from urban or rural areas, all showed obvious up trend （X2men = 60.88, x2women=13.72, X2urban = 17. 20, x2rural =54. 03, all P〈0.01） . More male patients died than females （x2 =3703.97, P〈0.01） and the mortality in urban area was significantly higher than that in rural area （x2= 28. 827, P〈0.01） . The top 10 malignant tumors were liver, lung, stomach, esophageal, co[orectal, leukemia, breast, nasopha- ryngeal, malignant lymphoma and pancreatic cancers. Liver cancer was the most common malignant tumor in male and in rural area while lung cancer was in female and in urban areas. Conclusions The mortality of malignant tumor shows an increasing trend. The malignant tumor surveillance in Fujian should be focused on liv- er, lung, stomach, esophageal and colorectal cancers. The control and prevention measures should be carried out according to gender, age, region distribution and prevalence trend.