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| 唑来膦酸钠治疗多发性骨髓瘤骨痛的疗效观察 | |
| 引用本文： | 吴小建,赖雪花,宋秋荷. 唑来膦酸钠治疗多发性骨髓瘤骨痛的疗效观察[J]. 临床和实验医学杂志, 2008, 7(9): 106-107 |
| 作者姓名： | 吴小建 赖雪花 宋秋荷 |
| 作者单位： | 1. 九江学院附属医院,血液科,江西,九江,332000 2. 九江学院护理学院,江西,九江,332000 3. 九江学院附属医院,皮肤科,江西,九江,332000 |
| 摘 要： | 目的观察唑来膦酸钠对多发性骨髓瘤骨痛的临床疗效。方法16例多发性骨髓瘤患者静脉点滴唑来膦酸钠4mg，每4周1次。结果唑来膦酸钠治疗组对骨痛的总有效率为87．5％，布桂嗪对照组治疗骨痛的总效率仅为37．5％。唑来膦酸钠无明显不良反应。结论唑来膦酸钠能有效缓解多发性骨髓瘤骨痛和活动功能障碍，并能协同化疗促进缓解、降低患者的高血钙水平。 |
| 关 键 词： | 多发性骨髓瘤 骨痛 膦酸类 治疗应用 |
To observe clinical efficiency of zoledronic acid for the treatment of multiple myeloma(MM) with oslalgia |
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| WU Xiao-jian,LAI Xue-hua,SONG Qiu-he. To observe clinical efficiency of zoledronic acid for the treatment of multiple myeloma(MM) with oslalgia[J]. Journal of Clinical and Experimental Medicine, 2008, 7(9): 106-107 | |
| Authors: | WU Xiao-jian LAI Xue-hua SONG Qiu-he |
| Affiliation: | WU Xiao-fian, LAI Xue - hua, SONG Qiu - he(1. Department of Blood section ; 2 Department of Dermetologe ; The Affdiated Hospital of Jiujiang University; 3 Department of Nusing College of JiuJiang University, JiuJiang Jiangxi 332000, China) |
| Abstract: | Objective To observe clinical efficiency of zoledronic acid for the treatment of multiple myeloma （MM） with oslalgia. Methods 16 patients with MM were given zoledronic acid 90rag for intravenous injection ,once every 2-4 weeks. Results The total effective rate of zole- dronic acid treatment group for ostalgia was 87.5% ,but AP -237control group was 37.5%. zoledronic acid had no obvious adverse reactions. Conclusion zoledronic acid can effectively relieve MM with ostalgia and functional disturbance ,as well as coordinating chemotherapy to relieve and decrease high calcium level of the patients. |
| Keywords: | Multiple myeloma Ostalgia Phosphonic acid Treatment and application |
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