2型糖尿病及其并发症中医临床疗效评价研究进展

随着人们生活水平的提高,2型糖尿病患者数量逐年增加,引起了医学界的高度重视,中医对此也进行了较多的探索。中医治疗2型糖尿病临床研究,对单纯2型糖尿病患者主要从血糖相关指标评价其疗效,另外胰岛素敏感指数、血脂、体重指数等也起到了一定的补充。对于2型糖尿病并发症,在注重血糖指标的基础上,还以各并发症相关指标为主进行疗效评价,如2型糖尿病肾损害的尿微量白蛋白,糖尿病心脑血管病的心功能指标,糖尿病周围神经病变之神经传导速度,糖尿病足之溃疡面积、肉芽生长情况,糖尿病视网膜病变之眼底检查等。除此类客观指标以外,症状积分和中医证候积分也是一个重要的评价指标。通过以上各种疗效评价指标,表明中医药治疗2型糖尿病及其并发症具有较好的疗效。但这些疗效评价标准仍存在不够统一,某些标准特异性不够等问题。

Progress on the clinical curative effect evaluation of traditional Chinese medicine treatment on type 2 diabetes and its complications

As living standard rising,the number of type 2 diabetes patients increases year by year.It caused the attention of the medical profession.Traditional Chinese medicine also did a lot of exploration.In clinical research on traditional Chinese medicine treatment for type 2 diabetes,to type 2 diabetes patients,blood glucose is the most common target to evaluate the efficacy,and insulin sensitive index,serum lipid,body mass index are also useful targets.For type 2 diabetes complications,not only blood glucose,but also the complications related indicators are mainly effect assessment,such as Urine micro albumin of type 2 diabetes renal damage,cardiac function index of diabetes cardio-cerebrovascular diseases,motor nerve conduction velocity of diabetes peripheral neuropathy,ulcer area,granulation growth of of diabetic foot,the fundus examination of diabetic retinopathy,etc.Besides such objective index,symptom integral and TCM syndrome integral are important evaluation index.Through the above curative effect evaluation,shows that Chinese medicine in the treatment of type 2 diabetes and its complications has good curative effect.But the curative effect evaluation standards still have some problems,such as the standards are not unified,and some are not specificity.