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| 系统性红斑狼疮生物疗药物浅谈 | |
| 引用本文： | 张文. 系统性红斑狼疮生物疗药物浅谈[J]. 中华临床免疫和变态反应杂志, 2012, 0(2): 85-87 |
| 作者姓名： | 张文 |
| 作者单位： | 中国医学科学院 北京协和医学院 北京协和医院风湿免疫科,北京100032 |
| 摘 要： | 近年来,生物靶向治疗越来越多地应用于自身免疫性疾病患者的治疗,并取得了较好的疗效。系统性红斑狼疮(SLE)是一种多系统受累的自身免疫病,患者体内存在多种免疫紊乱。目前治疗SLE的生物制剂包括去除B细胞、抑制T-B细胞间相互作用以及拮抗炎性细胞因子和B细胞活化因子等方面的药物。本文简要介绍已经上市和正在进行临床试验的SLE生物靶向治疗药物。 |
| 关 键 词： | 生物治疗 红斑狼疮,系统性 |
Biotherapy in Systemic Lupus Erythematosus |
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| ZHANG Wen. Biotherapy in Systemic Lupus Erythematosus[J]. Chinese Journal of Allergy and Clinical Immunology, 2012, 0(2): 85-87 | |
| Authors: | ZHANG Wen |
| Affiliation: | ZHANG Wen (Department of Rheumatology ＆ Clinical Immunology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences ＆ Peking Union Medical Collage,Beijing 100730,China |
| Abstract: | In recent years,biological therapy has increasingly been used in treating patients with autoimmune diseases.Systemic Lupus erythematosus（SLE） is a prototypic systemic autoimmune disease,characterized by disfunction of lymphocytes and production of various autoantibodies.Targeted biological agents for SLE include B cell depletion,interruption of T-B reaction,inhibition of pro-inflammatory cytokines or B cell activation factor,et al.Here we briefly introduce some promising biological agents for treating SLE patiens. |
| Keywords: | biological therapy lupus erythematosus,systemic |
| 本文献已被 CNKI 维普 等数据库收录！ | |