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| 血液病患儿细小病毒B_(19)感染的检测及临床意义 | |
| 引用本文： | 胡姣荣,张传湘,王军陵,王允鸿,吴冰,仲惟昆. 血液病患儿细小病毒B_(19)感染的检测及临床意义[J]. 中国小儿血液与肿瘤杂志, 1998, 0(4) |
| 作者姓名： | 胡姣荣 张传湘 王军陵 王允鸿 吴冰 仲惟昆 |
| 作者单位： | 湖北医科大学附属一院儿科研究所!430060(胡姣荣，张传湘，王允鸿，吴冰，仲惟昆)，湖北医科大学附属一院儿科(王军陵) |
| 摘 要： | 人细小病毒B19（HumanParvovirrusB19，HPVB19）与人类多种疾病密切相关，可通过接触和使用血液制品等在人群中传播［1］，本文采用聚合酶链反应（PCR）技术检测45例血液病患儿血清HPVB19－DNA，结果总阳性率为26．6％，其中急性白血病占38．8％（7／18），ITP占40．0％（4／10），过敏性紫癜占8．3％（1／12），再障5例均为阴性；同时检测对照组10名正常儿童均为阴性。将病例组与对照组进行比较有显著意义（P＜0．05）。 |
| 关 键 词： | 儿童血液病 HPVB_(19)－DNA PCR技术 |
THE DETECTION OF HUMAN PARVOVIRUS B_(19) IN CHILDREN WITH HEMATONOSIS AND ITS CLINICAL SIGNIFICANCE |
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| Abstract: | Human parvovirus B19 has close relation to mang kinds of disease. It can be spread inpopulation by contacting and using of blood products, people with immunodeficiency aremore susceptible to HPV B19 after blood transfusion or treatment with coagulation factorsthan general people. In this study, polymerase chain reaction technique been used to detectHPV B19-DNA in peripheral blood of 45 children suffering from hematonosis to investigateinfection rate of HPV B19. The results of this showed that the postitive rate is 26. 6%. Thedetection of HPV B19 has an important clinical significance.(Original article on page 159) |
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| 本文献已被 CNKI 等数据库收录！ | |