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Treatment of sphenoid dysplasia with a titanium-reinforced porous polyethylene implant in orbitofrontal neurofibroma: Report of three cases
Affiliation:1. Department of Plastic, Reconstructive and Aesthetic Surgery, Henri Mondor Hospital, University of Paris Est, France;2. Department of Neurosurgery, Henri Mondor Hospital, University of Paris Est, France;3. Department of Dermatology, Henri Mondor Hospital, University of Paris Est, France;4. Centre d''investigation Clinique Inserm 006 and EA 439, France;1. Department of Clinical Sciences, Faculty of Veterinary Medicine, Urmia University, Nazloo Road, Urmia 57153 1177, Iran;2. Department of Clinical Sciences, Faculty of Veterinary Medicine, Urmia Branch, Islamic Azad University, Urmia, Iran;3. Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4, Canada;1. Department of Head and Neck Surgery, Fuzhou General Hospital, Nanjing Command Zone of PLA, Fuzhou, China;2. Department of Bioinformatics, Fuzhou General Hospital, Nanjing Command Zone of PLA, Fuzhou, China;3. Department of Oncology, Fujian Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, 350112, China;1. Department of Plastic and Reconstructive Surgery, Chiba University, Graduate School of Medicine, Japan;2. Department of Neurosurgery, Showa University, Japan;1. Department of Plastic and Reconstructive surgery, Soonchunhyang University Hospital, 59 Daesagwan-ro, Yongsan-gu, Seoul, Republic of Korea;2. Department of Plastic and Reconstructive surgery, Hanyang University Guri Hospital, 153, Gyeongchun-ro, Guri-si, Gyeonggi-do, Republic of Korea
Abstract:
Orbital manifestations occur in less than 1% of patients with neurofibromatosis type 1 (NF1). These manifestations are frequently associated with sphenoid wing dysplasia. The typical radiologic feature is partial or total loss of the greater wing of the sphenoid bone, which leads to herniation of the temporal lobe through the orbital cavity resulting in proptosis and pulsating exophthalmos. Traditional reconstruction of this bone defect involves split bone grafting or titanium mesh. However, these techniques have some limitations due to bone resorption and infection risk. We report the use of 0.85 mm titanium-reinforced porous polyethylene implant sheet in three cases of orbital neurofibromatosis with sphenoid dysplasia. The role of this material was to create a barrier between the brain and orbital cavity. The implant sheet was modeled intraoperatively to reconstruct the orbital cavity anatomy and fitted without any screws. The malleability of the implant allows quick reconstruction of the curved orbital skeleton. Furthermore, the implant doesn't interfere with postoperative imaging and may decrease risk infection.
Keywords:Neurofibromatosis  Sphenoid dysplasia  Porous polyethylene implant  Titanium mesh  Bone grafts
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