Mitochondrial mutagenesis in Saccharomyces cerevisiae

Summary Four types of mit^– mutations induced with manganese are found in the following relative proportions: oxi3^– > cob-box^– > oxi2^– oxi1^–1. The frequences of loss of their respective mit⁺ alleles in manganese-induced rho^–] primary and secondary clones follow the same order. The possible interdependence between these two sets of data is discussed.