颈动脉粥样硬化超声检测和冠状动脉粥样硬化的相关性分析

目的:评价颈动脉粥样硬化对冠状动脉粥样硬化的预测价值,并寻找与颈动脉硬化有关的因素。方法:选择冠状动脉造影后62例患者,行颈动脉超声检查,观察颈动脉内-中膜状况,以所测最大内中膜厚度及斑块发生率为观察指标。同时作血脂生化分析。用SPSS11.0软件包进行统计学分析。结果:冠状动脉造影正常组与病变组之间、病变组之间颈动脉斑块面积、斑块积分、斑块数目、IMT比较有显著差异(P<0.05)。冠状动脉造影结果与颈动脉超声斑块形成结果比较,颈动脉超声的敏感性为82.4(42/51),特异性为72.7%(8/11),总的诊断符合率为82.3%(51/62)。逐步Logistic回归分析,显示年龄、血压、血糖、TG及HDL-ch与IMT有相关性。结论:颈动脉粥样硬化与冠状动脉粥样硬化病变之间有着显著的相关性,提示颈动脉壁内—中膜厚度及斑块能反映冠状动脉粥样硬化程度。

Analysis of the ultrasound scanning parameters in carotid and coronary artery atherosclerosis

Objective:The aim of this study was to use high-resolution ultrasonography to evaluate clinical value of carotid atherosclerosis,to predict coronary artery disease and to analyse the influence of vascular risk factors on carotid artery atherosclerosis.Methods:Carotid ultrasound was performed in 62 patients who had been consecutively examined by coronary angiography,carotid plaque score was also calculated to quantify the extent of carotid atherosclerosis.Meanwhile,we collected risk factors such as glucose,plasma total cholesterol,low density lipoprotein and high density lipoprotein level,and difined as carotid atherosclerosis.Multivariate analysis was performed to evaluate the relationship between risk factors and carotid atherosclerosis.Results:The more serious the coronary artery disease,the thicker maximum intima-media thickness and the more plaque number,score,area in carotid artery were.There was a statistically significant value.Carotid atherosclerosis reflected coronary artery disease with a sensitivity,specificity and accuracy value of 82.4%(42/51),72.7%i(8/11),82.3%(51/62),respectively.Logistic models indicated that age,blood pressure,glucose,TG and HDL-ch were significant variables.Conclusion:There is a strong and significant relation between carotid artery atherosclerosis and coronary artery disease.Also,there are similar risk factors between them.Carotid artery atherosclerosis is a marker relevant to coronary artery disease which can be measured non-invasively.