2型糖尿病患者及非糖尿病人群的踝臂指数与高血压相关性研究

目的探讨2型糖尿病患者及非糖尿病人群中高血压与踝臂指数(ABI)的相关性。方法选取124例2型糖尿病患者作为糖尿病组,本院体检的122例非2型糖尿病体检人群作为对照组。比较两组人群高血压及非高血压人群的踝臂指数,同时分析两组人群ABI与收缩压、舒张压的简单线性相关性。最后运用Logistic回归研究两组人群高血压与ABI的相关性。结果两组人群ABI存在显著差异(P<0.05)。在糖尿病组,ABI在高血压人群与非高血压人群存在显著差异,而且,ABI与收缩压及舒张压均存在简单相关性(P<0.05)。在非校正模式及校正年龄、性别、总胆固醇、HDL、LDL、甘油三酯、BMI、腰围等影响因素后,高血压是ABI的独立危险因素(P<0.05)。但在非糖尿病人群中,均未发现上述相关性。结论 2型糖尿病患者中,高血压与反映外周动脉硬化的踝臂指数独立相关。

Correlation Study of Hypertension and Ankle-Brachial Index in Type 2 Diabetes Mellitus Patients and Physical Examination People Without Diabetes

Objective To investigate the correlation of hypertension and ankle-brachial index in type 2 diabetes mellitus patients and physical examination people without diabetes. Methods 124 patients with type 2 diabetes mellitus were selected as diabetic group, 122 cases of non-diabetic population did physical examination in our hospital were selected as control group. The ABI of non-hypertensive patients and hypertensive patients were compared, the simple linear correlation between the ABI and systolic blood pressure, diastolic blood pressure were analyzed. Logistic regression was used to study the correlation of hypertension and ABI. Results ABI showed statistically significant difference in two groups （P 〈0.05）. In the diabetic group, ABI showed significant difference in the hypertensive population and non-hypertensive population. Moreover, ABI had simple linear correlation with systolic and diastolic blood pressure （P 〈0.05）. In non-adjusted model and model with age, gender, total cholesterol, HDL, LDL, triglycerides, BMI, waist circumference were revised, hypertension was an independent risk factor to ABI （P 〈0.05）. But in the non-diabetic population, such correlation was not found. Conclusions In type 2 diabetes mellitus patients, hypertension is independently associated with ABI, which reflects the peripheral arteriosclerosis.