190 例胃癌患者中医证型与血清EGF 水平的相关性研究

探讨胃癌患者辨证分型与血清表皮生长因子（EGF）水平之间的关系。方法：临床收集190 例不同证型胃癌患者，ELISA 测定血清EGF 水平，SPSS 16.0 软件分析胃癌证型与血清EGF 水平的相关性。结果：痰浊凝滞证与脾胃虚弱、胃热阴伤、气阴两虚、湿热蕴毒以及瘀血内阻证之间有统计学差异（P<0.05）。性别分层分析显示，男性痰浊凝滞证与脾胃虚弱、胃热阴伤、湿热蕴毒以及瘀血内阻证之间有统计学差异（P<0.05）。结论：血清EGF 水平与胃癌患者辨证分型可能存在相关性。

Study on Correlation between Traditional Chinese Medicine Syndrome and EGF Serum Level among 190 Gastric Carcinoma Cases

This study was aimed to explore the correlation between traditional Chinese medicine(TCM) syndrome and epidermal growth factor (EGF) serum level among gastric carcinoma cases. A total of 190 gastric carcinoma cases with different syndromes had been collected. ELISA was used in the determination of EGF serum level. Correlations between TCM syndromes of gastric cancer and EGF serum levels were analyzed by SPSS 16.0 software. The results showed that there were statistical differences between the syndrome of turbid-phlegm stagnation and syndrome of spleen-stomach deficiency, syndrome of stomach-heat and yin-damaging, syndrome of qi-yin deficiency, syndrome of damp-heat with toxin-accumulation, syndrome of blood-stasis blockage (P < 0.05). Gender stratification analysis showed that there were statistical differences between the syndrome of turbid-phlegm stagnation and syndrome of spleen-stomach deficiency, syndrome of stomach-heat and yin-damaging, syndrome of damp-heat with toxin-accumulation, syndrome of blood-stasis blockage among male cases (P < 0.05). It was concluded that the EGF serum level may be correlated with syndrome differentiation of gastric carcinoma cases.