| 嗜酸粒细胞型鼻息肉患者血清特异性IgE检测的临床分析 |
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| 引用本文： | 徐明,赵枫,沈安民,周浩杰. 嗜酸粒细胞型鼻息肉患者血清特异性IgE检测的临床分析[J]. 临床耳鼻咽喉头颈外科杂志, 2012, 0(17): 772-773 |
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| 作者姓名： | 徐明 赵枫 沈安民 周浩杰 |
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| 作者单位： | 宁波大学医学院附属医院耳鼻咽喉科;宁波大学医学院附属医院检验中心;宁波大学医学院附属医院病理科 |
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| 摘 要： | 目的:探讨不同类型鼻息肉(NP)患者对吸入性变应原的超敏性及相关性。方法:将83例NP患者按息肉标本内嗜酸粒细胞(EOS)计数多少分为嗜酸粒细胞型鼻息肉(ENP)和非嗜酸粒细胞型鼻息肉(nENP),所有NP患者进行血清变应原特异性IgE(sIgE)检测及统计学分析。结果:ENP和nENP患者分别为27例(32.53%)、56例(67.47%),其血清变应原sIgE阳性者分别为16例(59.26%)、13例(23.21%),2种类型间比较差异有统计学意义(P<0.01);尘螨是NP组最常见的变应原。结论:常年性吸入性变应原与ENP患者有相关性。
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| 关 键 词： | 变应原 嗜酸粒细胞 变态反应 鼻息肉 |
Serum allergen-specific IgE in patients with eosinophilic nasal polyps |
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| XU Ming,ZHAO Feng,SHEN Anmin,ZHOU Haojie. Serum allergen-specific IgE in patients with eosinophilic nasal polyps[J]. Journal of clinical otorhinolaryngology, head, and neck surgery, 2012, 0(17): 772-773 |
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| Authors: | XU Ming ZHAO Feng SHEN Anmin ZHOU Haojie |
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| Affiliation: | 1Department of Otorhinolaryngology,the Affiliated Hospital,Medical School of Ningbo University,Ningbo,315020,China;2Department of Ecsomatics,the Affiliated Hospital,Medical School of Ningbo University;3Department of Pathology,the Affiliated Hospital,Medical School of Ningbo University) |
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| Abstract: | Objective:To investigate the relationship between airborne allergen and patients with nasal polyps(NP).Method:Eighty-three cases of patients with NP were classified into the eosinophilic group(ENP) and non eosinophilic group(nENP) in terms of the EOS count in NP specimen,all patients underwent specific-IgE test with standardized allergens and the results were analyzed.Result:The specific-IgE positive rate was 59.26% in ENP group and 23.21% in the nENP group respectively(P<0.01),and the positive rate of ENP was statistical significance compared with nENP.The dust mite was the most prevalent airborne allergen in ENP group.Conclusion:The perennial airborne allergens may play a certain role in the etiology and pathogenesis of NP. |
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| Keywords: | allergens eosinophils allergy nasal polyps |
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