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心房颤动口服药物治疗的新选择
引用本文:陈家元,张爱东,卢红艳,李自成. 心房颤动口服药物治疗的新选择[J]. 临床心血管病杂志, 2012, 0(9): 646-648
作者姓名:陈家元  张爱东  卢红艳  李自成
作者单位:暨南大学附属第一医院心内科
基金项目:暨南大学第一临床医学院重点学科基金(No:暨一临【2010】4号)
摘    要:
近年来,尽管导管消融和外科手术在心房颤动(房颤)的治疗中取得了令人瞩目的进展,但并未广泛应用,药物治疗依然处于首要地位。由于传统抗凝药和抗心律失常药的自身局限性,该领域新型药物的开发成为研究热点,而近年来多种新型口服药物的开发研制和临床试验的成功,为房颤的药物治疗带来新的希望。本文对此加以综述。

关 键 词:心房颤动  达比加群酯  利伐沙班  决奈达隆

New option in oral drug for the treatment of atrial fibrillation
CHEN Jiayuan,ZHANG Aidong,LU Hongyan,LI Zicheng. New option in oral drug for the treatment of atrial fibrillation[J]. Journal of Clinical Cardiology, 2012, 0(9): 646-648
Authors:CHEN Jiayuan  ZHANG Aidong  LU Hongyan  LI Zicheng
Affiliation:(Department of Cardiology,First Affiliated Hospital of Jinan University,Guangzhou,510630,China)
Abstract:
Although catheter ablation technology and surgery treatment of atrial fibril-ation have been remarked advance in recent years,the application is limited,and drug therapy is still the first choice.Owing to the limitation of traditional anticoagulation and antiarrhyt-hmic drug,it becomes a hot spot to develop new durgs in this field.Recently the successes of development and clinic trials of novel oral anticoagulant and antiarrhythmic drugs bring a new hope for treatment of atrial fibrillation.This review discusses recent advances about these new drugs.
Keywords:atrial fibrillation  dabigatran etexilate  rivaroxaban  dronedarone
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