| 替米沙坦不同时间给药治疗非杓型高血压疗效观察 |
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| 引用本文： | 吴圣利,王瑞听,项延郡,张治平,章志东,李道在. 替米沙坦不同时间给药治疗非杓型高血压疗效观察[J]. 中国药房, 2011, 0(14) |
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| 作者姓名： | 吴圣利 王瑞听 项延郡 张治平 章志东 李道在 |
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| 作者单位： | 浙江苍南县第三人民医院心内科; |
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| 基金项目： | 浙江省苍南县科技局课题项目(2009S24) |
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| 摘 要： | 目的:观察替米沙坦不同时间给药治疗非杓型高血压的疗效。方法:80例非杓型轻、中度原发性高血压患者随机分为晨服组与晚服组,2组均服用替米沙坦。晨服组于7∶00时给予替米沙坦(80 mg/片)1片,每日1次;晚服组于19∶00时给予替米沙坦(80 mg/片)1片,每日1次。12周后复查动态血压,比较2组血压昼夜节律的变化。结果:晨服组将非杓型血压纠正为杓型血压恢复昼夜节律的比例为20.0%,而晚服组将非杓型血压纠正为杓型血压恢复昼夜节律的比例为52.5%,2组间差异有统计学意义(P<0.01)。晚服组清晨时段(5∶00-9∶00)收缩压和舒张压显著低于晨服组(P<0.05)。结论:对于非杓型高血压患者,时辰化服用替米沙坦可以更好地改善血压昼夜节律。
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| 关 键 词： | 非杓型高血压 动态血压 替米沙坦 |
Efficacy Observation of Telmisartan at Different Administration Time in the Treatment of Non-dipper Hypertension |
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| WU Sheng-li,WANG Rui-ting,XIANG Yan-jun,ZHANG Zhi-ping,ZHANG Zhi-dong,LI Dao-zai. Efficacy Observation of Telmisartan at Different Administration Time in the Treatment of Non-dipper Hypertension[J]. China Pharmacy, 2011, 0(14) |
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| Authors: | WU Sheng-li WANG Rui-ting XIANG Yan-jun ZHANG Zhi-ping ZHANG Zhi-dong LI Dao-zai |
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| Affiliation: | WU Sheng-li,WANG Rui-ting,XIANG Yan-jun,ZHANG Zhi-ping,ZHANG Zhi-dong,LI Dao-zai(Dept.of Cardiology,Cangnan County Third People's Hospital of Zhejiang Province,Cangnan 325804,China) |
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| Abstract: | OBJECTIVE:To observe the therapeutic efficacy of telmisartan at different administration time in the treatment of non-dipper hypertension.METHODS:A total of 80 patients with mild to moderate essential hypertension(EH) were randomly divided into morning administration group and evening administration group.Both groups were given telmisartan.Morning administration group were treated with telmisartan 80 mg at 7 am in the morning once a day;evening administration group were treated with telmisartan 80 mg at 19 ... |
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| Keywords: | Non-dipper hypertension Ambulatory blood pressure Telmisartan |
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