| 《中国药学文摘》收录的抗菌药物致不良反应统计分析 |
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| 引用本文： | 曹芳,周燕娥. 《中国药学文摘》收录的抗菌药物致不良反应统计分析[J]. 中国药房, 2011, 0(10): 917-919 |
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| 作者姓名： | 曹芳 周燕娥 |
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| 作者单位： | 平凉医学高等专科学校;甘肃省临洮县城关中心卫生院; |
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| 摘 要： | 目的:统计分析抗菌药物引起药品不良反应(ADR)的情况,以有效预防和减少ADR的危害,提高ADR的监测能力。方法:对2008-2009年《中国药学文摘》收录的抗菌药物致ADR文献进行检索。通过Excel电子表对发生ADR的药品种类、给药途径、累及器官或系统及临床表现、ADR发生例数居前10位药品进行回顾性统计、分析。结果:抗菌药物致ADR报道篇数1249篇,病例656例,涉及药品123种。以头孢菌素类(18.90%)发生例次最多,其次为喹诺酮类(16.16%)、青霉素类(14.18%);静脉滴注最易导致ADR(81.10%);ADR临床主要表现为皮肤及其附件损害(19.05%),其次为消化系统损害(16.31%)和中枢或外周神经系统损害(14.63%);左氧氟沙星的ADR发生率最高(89例)。结论:临床应加强对抗菌药物致ADR的重视和监测工作,以保证用药的安全性。
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| 关 键 词： | 抗菌药物 药品不良反应 统计分析 中国药学文摘 |
Statistical Analysis of Antimicrobial Drug-induced ADR Recorded in Chinese Pharmaceutical Abstracts |
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| CAO Fang ZHOU Yan-e. Statistical Analysis of Antimicrobial Drug-induced ADR Recorded in Chinese Pharmaceutical Abstracts[J]. China Pharmacy, 2011, 0(10): 917-919 |
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| Authors: | CAO Fang ZHOU Yan-e |
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| Affiliation: | CAO Fang(Pingliang Medical College,Pingliang 744000,China) ZHOU Yan-e(Lintao County Central Health Center of Gansu Province,Lintao 730500,China) |
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| Abstract: | OBJECTIVE:To analyze antimicrobial drug-induced adverse drug reactions(ADR) in order to effectively prevent and reduce ADR and improve ADR monitoring.METHODS:Antimicrobial drug-induced ADR recorded in Chinese Pharmaceutical Abstracts during 2008-2009 were retrieved.The types of drugs,routes of administration,organ or system involved and clinical manifestations,top 10 antimicrobial drugs in the list of the number of ADR cases were analyzed retrospectively using Excel.RESULTS:There were 1 249 literatures on a... |
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| Keywords: | Antimicrobial drug Adverse drug reaction Statistical analysis Chinese Pharmaceutical Abstracts |
| 本文献已被 CNKI 维普 等数据库收录！ |
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