醒脑静注射液治疗急性脑梗死的临床疗效及CT观察

目的 :探讨醒脑静注射液治疗急性脑梗死的疗效及 CT的表现。方法 :86例急性脑梗死患者随机分为两组。两组在常规治疗中 ,治疗组 45例用醒脑静注射液 30 m L 加生理盐水 2 5 0 m L 静滴 ,对照组 41例用复方丹参注射液 16 m L 加生理盐水 2 5 0 m L 静滴 ,两组均每日 1次 ,连用 14天。结果 :治疗组治疗后第 5天 N DS评分较治疗前有显著性差异( P<0 .0 1) ,与对照组治疗后第 5天 NDS评分比较也有显著性差异 ( P <0 .0 1) ;治疗组与对照组的总有效率分别为 82 .2 2 %和 80 .6 5 % ( P >0 .0 5 ) ,但显效率分别为 6 2 .2 2 %和 38.70 %有显著性差异 ( P <0 .0 1) ;治疗组 CT复查示病灶改善、好转 30例 ,好转率 6 6 .6 7% ,显著优于对照组 41.94% ( P <0 .0 5 )。结论 :醒脑静注射液治疗急性脑梗死在早期能减轻梗死区的水肿 ,缩小病变范围 ,且有醒脑开窍 ,清热化痰能促进神经功能恢复的作用 ,疗效肯定 ,无不良反应

The clinical efficacy and CT evaluation for treatment of acute brain infarction with Xingnaojing injection

Objective:It is to study on the efficacy and CT manifestations of treatment of acute brain infarction with Xingnaojing injection. Methods: 86 cases of Acute brain infarction were randomly grouped into 2 branches. For routine medication, each of 45 patients as the treatment group was given Xingnaojing injection 30mL plus NS 250mL intravenously and each of 11 patients as the control groups was given injection salviae miltiorrhizae composita 16mL plus NS 250mL intravenously. The both group were dosed daily, lasting 14 days. Results: The 5th day NDS scores in the treatment group were significantly improved (P<0.01)and better than that in the control group (P<0.01). Despite that the total rate of effectiveness in the treatment group was 82.22% vs 80.65% in the control group (P>0.05), the rate of significant effectiveness was 62.22% in the treatment group vs 38.70% in the control group (P<0.01), CT evaluation indicated improvement of brain foci 30 patients in the treatment group with 66.67 % as the improvement rate vs 41.94% as that in the control group (P<0.05). Conclusion:Xingnaojing injection relieves edema at the foci during early stage of acute brain infarction and reduces the area of lesion. Thus, it is definitely effective and without any adverse effects for neural function recovery with a TCM mechanism of brain resuscitation and eliminating phlegm by cooling. ;